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CAS 844439-96-9

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Insulin degludec

Description:
Insulin degludec is a long-acting insulin analog used primarily in the management of diabetes mellitus. It is characterized by its unique molecular structure, which includes a modification that allows for a prolonged duration of action compared to regular insulin. This modification involves the addition of a fatty acid chain, enabling the formation of multi-hexamers in subcutaneous tissue, leading to a slow and steady release into the bloodstream. Insulin degludec has a relatively flat pharmacokinetic profile, which helps to minimize the risk of hypoglycemia and allows for flexible dosing schedules. It is typically administered via subcutaneous injection and can be used in combination with other antidiabetic medications. The onset of action is gradual, with effects lasting up to 42 hours, making it suitable for once-daily dosing. As with other insulin therapies, monitoring blood glucose levels is essential to ensure effective glycemic control while minimizing potential side effects. Overall, insulin degludec represents a significant advancement in diabetes management, providing patients with improved flexibility and stability in blood glucose regulation.
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