CAS 844441-56-1

1H-Pyrazole-3-carboxamide, 4-[(2,6-difluorobenzoyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-

Description:

1H-Pyrazole-3-carboxamide, 4-[(2,6-difluorobenzoyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]- is a synthetic organic compound characterized by its pyrazole core, which is a five-membered ring containing two nitrogen atoms. This compound features a carboxamide functional group, contributing to its potential as a bioactive molecule. The presence of a difluorobenzoyl moiety enhances its lipophilicity and may influence its biological activity. Additionally, the tetrahydro-2H-pyran substituent introduces a cyclic ether structure, which can affect the compound's solubility and interaction with biological targets. The overall molecular structure suggests potential applications in medicinal chemistry, particularly in drug development, due to its unique combination of functional groups that may interact with specific biological pathways. The compound's CAS number, 844441-56-1, allows for easy identification and retrieval of information in chemical databases. As with many synthetic compounds, its properties, such as solubility, stability, and reactivity, would need to be characterized through experimental studies to fully understand its potential applications.

Formula: C₁₇H₁₈F₂N₄O₃

Synonyms:

• 1H-Pyrazole-3-carboxamide, 4-[(2,6-difluorobenzoyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-

GSK3-IN-10

CAS: 844441-56-1

GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.

Formula: C₁₇H₁₈F₂N₄O₃

Color and Shape: Solid

Molecular weight: 364.347

Ref: TM-T206481