CAS 844496-96-4

tert-Butyl (1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)carbamate

Controlled Product

CAS: 844496-96-4

Applications tert-Butyl (1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)carbamate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.
References Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)

Formula: C₂₄H₄₁NO₄

Color and Shape: Neat

Molecular weight: 407.587

Ref: TR-B943078