CAS 84485-00-7

Sibutramine hydrochloride

Description:

Sibutramine hydrochloride is a synthetic compound primarily used as an appetite suppressant in the management of obesity. It functions as a serotonin-norepinephrine reuptake inhibitor (SNRI), enhancing the levels of these neurotransmitters in the brain, which helps to reduce hunger and increase feelings of fullness. The substance is typically presented as a white to off-white crystalline powder, soluble in water and alcohol, with a molecular formula that reflects its complex structure. Sibutramine was once widely prescribed but has been withdrawn from many markets due to concerns over cardiovascular risks, including increased blood pressure and heart rate. Its pharmacokinetics indicate that it is metabolized in the liver, with active metabolites contributing to its effects. Despite its previous popularity, the safety profile of sibutramine has led to a reevaluation of its use, emphasizing the importance of monitoring and managing potential side effects in patients. As of now, it is essential to consult healthcare professionals regarding its use and to consider alternative weight management strategies.

Formula: C₁₇H₂₆ClN·ClH

InChI: InChI=1S/C17H26ClN.ClH/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;/h6-9,13,16H,5,10-12H2,1-4H3;1H

InChI key: InChIKey=UWAOJIWUVCMBAZ-UHFFFAOYSA-N

SMILES: C(CC(C)C)(N(C)C)C1(CCC1)C2=CC=C(Cl)C=C2.Cl

Synonyms:

• 1-(4-Chlorophenyl)-N,N-Dimethyl-Beta-(2-Methylpropyl)Cyclobutanemethanamine Hydrochloride
• 1-[2-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine
• Bts 54524
• Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride
• Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride (1:1)
• Meridia
• Reductil
• Redulip
• Sibutramin hydrochloride
• Sibutramine Hcl
• Sibutraminehydrochloride
• Sibutramine・HCL

Sibutramine HCl

CAS: 84485-00-7

Formula: C₁₇H₂₆ClN·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 279.86 36.46

Ref: 4Z-S-051

Sibutramine hydrochloride

Controlled Product

CAS: 84485-00-7

Formula: C₁₇H₂₆ClN·ClH

Color and Shape: Neat

Molecular weight: 316.31

Ref: 04-C16944000

Sibutramine hydrochloride

Controlled Product

CAS: 84485-00-7

Serotonin receptor 5-HT antagonist; noradrenaline reuptake inhibitor

Formula: C₁₇H₂₆ClN•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 316.31 g/mol

Ref: 3D-FS46542