CAS 845272-21-1

ARRY-334543

Description:

As of my last update in October 2023, specific information about the chemical substance ARRY-334543, with the CAS number 845272-21-1, is limited in publicly available databases. Generally, substances with such identifiers are often in the realm of pharmaceutical research or development, potentially serving as experimental compounds in drug discovery. Characteristics of such compounds typically include their molecular structure, solubility, stability, and biological activity, which are crucial for understanding their potential applications and safety profiles. Researchers often investigate these properties through various analytical techniques, including spectroscopy and chromatography, to determine their efficacy and mechanism of action. If ARRY-334543 is a novel compound, detailed information may be found in scientific literature or patent filings, which would provide insights into its synthesis, pharmacodynamics, and potential therapeutic uses. For the most accurate and comprehensive data, consulting specialized databases or recent publications would be advisable.

Synonyms:

• Arry334543
• Varlitinib

ARRY-334543

CAS: 845272-21-1

Formula: C₂₂H₁₉ClN₆O₂S

Purity: 96%

Color and Shape: Solid

Molecular weight: 466.9433

Ref: IN-DA00G3QD

Varlitinib

CAS: 845272-21-1

Varlitinib

Purity: ≥98%

Molecular weight: 466.94g/mol

Ref: 54-BUP03009

Varlitinib

CAS: 845272-21-1

Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.

Formula: C₂₂H₁₉ClN₆O₂S

Purity: 99.7%

Color and Shape: Solid

Molecular weight: 466.94

Ref: TM-T6719

Varlitinib

Controlled Product

CAS: 845272-21-1

Formula: C₂₂H₁₉ClN₆O₂S

Color and Shape: Neat

Molecular weight: 466.943

Ref: TR-V099100

Varlitinib

CAS: 845272-21-1

Varlitinib is a small molecule tyrosine kinase inhibitor, which is derived from synthetic chemical processes. Its mode of action involves the selective inhibition of the human epidermal growth factor receptor (HER) family, including EGFR, HER2, and HER4, thereby disrupting key signaling pathways involved in cancer cell proliferation and survival. This multi-targeted approach allows Varlitinib to effectively impede the growth and spread of cancer cells by interfering with critical intracellular signaling networks.

Formula: C₂₂H₁₉ClN₆O₂S

Purity: Min. 95%

Molecular weight: 466.94 g/mol

Ref: 3D-VIB27221