CAS 84558-94-1

5-(1-Propynyl)-2′-deoxyuridine

Description:

5-(1-Propynyl)-2′-deoxyuridine, also known by its CAS number 84558-94-1, is a nucleoside analog that features a propynyl group at the 5-position of the uridine base. This modification enhances its potential as an antiviral agent, particularly against certain viruses by interfering with viral replication. The compound retains the characteristic pyrimidine structure of uridine, which consists of a uracil base linked to a deoxyribose sugar. Its unique propynyl substitution contributes to its biological activity, making it a subject of interest in medicinal chemistry and virology. The compound is typically studied for its pharmacological properties, including its mechanism of action, efficacy, and potential side effects. As a nucleoside analog, it may also exhibit incorporation into viral RNA or DNA, thereby disrupting normal nucleic acid synthesis. Overall, 5-(1-Propynyl)-2′-deoxyuridine represents a significant area of research in the development of antiviral therapies.

Formula: C₁₂H₁₄N₂O₅

InChI: InChI=1S/C12H14N2O5/c1-2-3-7-5-14(12(18)13-11(7)17)10-4-8(16)9(6-15)19-10/h5,8-10,15-16H,4,6H2,1H3,(H,13,17,18)/t8-,9+,10+/m0/s1

InChI key: InChIKey=HFJMJLXCBVKXNY-IVZWLZJFSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C#CC)C(=O)N1

Synonyms:

• 2′-Deoxy-5-(1-propyn-1-yl)uridine
• 5-(1-Propynyl)-2'-deoxyuridine
• Uridine, 2′-deoxy-5-(1-propynyl)-
• Uridine,2'-deoxy-5-(1-propynyl)- (9CI)
• 1: PN: US20040009933 PAGE: 16 claimed sequence
• Uridine, 2′-deoxy-5-(1-propyn-1-yl)-

2'-Deoxy-5-propynyluridine

CAS: 84558-94-1

2'-Deoxy-5-propynyluridine is a nucleoside that is naturally synthesized in the body. It is an intermediate in the synthesis of pyrimidine nucleotides and has been shown to be useful for the treatment of cardiac arrhythmias. 2'-Deoxy-5-propynyluridine has also been found to have a stabilizing effect on RNA, enhancing its biological relevance. This compound can be used as a fluorescent probe and can be used to study transcriptional regulation mechanisms.

Formula: C₁₂H₁₄N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 266.26 g/mol

Ref: 3D-ND02838