CAS 845714-00-3

2-pyridin-4-yl-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride

Description:

2-Pyridin-4-yl-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride is a chemical compound characterized by its complex bicyclic structure, which includes both pyridine and pyrrolo moieties. This compound typically exhibits properties associated with heterocyclic compounds, such as potential biological activity, making it of interest in medicinal chemistry. The presence of the pyridine ring suggests it may engage in hydrogen bonding and participate in various chemical reactions, while the tetrahydro-pyrrolo structure contributes to its overall stability and solubility. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, enhancing its utility in pharmaceutical applications. The compound may exhibit specific pharmacological properties, potentially acting as an inhibitor or modulator in biological systems, although detailed studies would be necessary to elucidate its exact mechanisms of action. Safety and handling precautions should be observed, as with any chemical substance, particularly in laboratory or industrial settings.

Formula: C₁₂H₁₁N₃O·ClH

InChI: InChI=1/C12H11N3O.ClH/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12;/h1-2,4-5,7,15H,3,6H2,(H,14,16);1H

SMILES: c1cnccc1c1cc2c(CCN=C2O)[nH]1.Cl

Synonyms:

• Pha-767491
• PHA-767491 (CAY10572)
• CS-229
• 2-(pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one
• CAY10572
• PHA 767491 HYDROCHLORIDE
• PHA 767491 HYDROCHLORIDE USP/EP/BP
• PHA-767491HCL
• 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-onehydrochloride
• 4H-Pyrrolo[3,2-c]pyridin-4-one, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-
• CAY10572(PHA-767491)
• 2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
• PHA 767491;PHA-767491
• 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one

1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one

CAS: 845714-00-3

Formula: C₁₂H₁₁N₃O

Purity: 98%

Molecular weight: 213.2352

Ref: IN-DA0038EM

PHA-767491

CAS: 845714-00-3

PHA-767491

Purity: ≥98%

Molecular weight: 213.24g/mol

Ref: 54-BUP13110

PHA-767491

CAS: 845714-00-3

PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.

Formula: C₁₂H₁₁N₃O

Purity: 99.49% - >99.99%

Color and Shape: Solid

Molecular weight: 213.24

Ref: TM-T6206

PHA 767491

CAS: 845714-00-3

PHA 767491 is a selective cyclin-dependent kinase (CDK) inhibitor, which is a synthetic compound derived from pharmaceutical research. It functions primarily by inhibiting CDK7 and CDK9, which play a crucial role in cell cycle regulation and transcriptional control. By targeting these kinases, PHA 767491 effectively halts the proliferation of cancer cells, making it a valuable tool in cancer research.

This compound has been widely used in preclinical studies to explore the mechanisms of cell cycle arrest and apoptosis in various cancer cell lines. Additionally, its application extends to understanding transcriptional regulation in oncogenesis. The high selectivity and potency of PHA 767491 provide researchers with a precise means of dissecting CDK-mediated pathways, contributing to the development of more targeted cancer therapies.

Formula: C₁₂H₁₁N₃O

Purity: Min. 95%

Molecular weight: 213.24 g/mol

Ref: 3D-VIB71400