CAS 84573-16-0

(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide

Description:

The chemical substance with the name "(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide" and CAS number 84573-16-0 is a complex organic compound characterized by its multi-ring structure, which includes a cyclopenta[b]benzofuran core. This compound features multiple functional groups, including hydroxyl (-OH), methoxy (-OCH3), and amide (-CON(CH3)2) groups, contributing to its potential biological activity. The stereochemistry indicated by the IUPAC name suggests specific spatial arrangements of atoms, which can influence the compound's interactions with biological targets. Such compounds are often studied for their pharmacological properties, including potential therapeutic effects. The presence of methoxy and phenyl groups may enhance lipophilicity, affecting solubility and permeability. Overall, this substance exemplifies the complexity and diversity of organic molecules, particularly in medicinal chemistry, where structural variations can lead to significant differences in biological activity and efficacy.

Formula: C₂₉H₃₁NO₇

InChI: InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3/t23-,24-,26-,28+,29+/m1/s1

InChI key: InChIKey=DAPAQENNNINUPW-IDAMAFBJSA-N

SMILES: O[C@]12[C@]([C@@H]([C@@H](C(N(C)C)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(OC)C4)C5=CC=C(OC)C=C5

Synonyms:

• Rocaglamide
• 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, [1R-(1α,2α,3β,3aβ,8bβ)]-
• NSC 326408
• (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide
• 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-

Rocaglamide

CAS: 84573-16-0

Formula: C₂₉H₃₁NO₇

Purity: 99%

Color and Shape: Solid

Molecular weight: 505.5589

Ref: IN-DA008HI1

pGlu-K(-NBD)-Q-R-L-G-N-Q-W-A-V-G-H-L-M-N

CAS: 84573-16-0

pGlu-K(-NBD)-Q-R-L-G-N-Q-W-A-V-G-H-L-M-N

Purity: ≥98%

Molecular weight: 1910.08g/mol

Ref: 54-BUP20560

Rocaglamide

CAS: 84573-16-0

Formula: C₂₉H₃₁NO₇

Molecular weight: 505.56

Ref: 7W-GX5796

Rocaglamide

CAS: 84573-16-0

Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.

Formula: C₂₉H₃₁NO₇

Purity: 95.32% - 99.67%

Color and Shape: Solid

Molecular weight: 505.56

Ref: TM-TQ0131

Rocaglamide

Controlled Product

CAS: 84573-16-0

Applications Rocaglamide is derived from a Chinese medicinal plant Aglaia. Rocaglamide induces apoptosis in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells freshly isolated from patients.
References Zhu, J., et. al.: Int. J. Cancer, 121, 1839 (2007)

Formula: C₂₉H₃₁NO₇

Color and Shape: Neat

Molecular weight: 505.559

Ref: TR-R639450