CAS 84624-17-9

fmoc-D-valine

Description:

Fmoc-D-valine is a derivative of the amino acid valine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protective group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group of the amino acid while allowing for the coupling of other amino acids. Fmoc-D-valine is a white to off-white solid that is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but is generally insoluble in water. The Fmoc group can be removed under basic conditions, typically using a solution of piperidine, which regenerates the free amino group for further reactions. The D-configuration of valine in this compound is significant in the context of peptide synthesis, as it can influence the structure and biological activity of the resulting peptides. Overall, Fmoc-D-valine is a valuable building block in the field of medicinal chemistry and peptide research.

Formula: C₂₀H₂₁NO₄

Synonyms:

• N-(9-fluorenylmethoxycarbonyl)-D-valine
• Fmoc-D-Val-OH
• NALPHA-9-Fluorenylmethoxycarbonyl-D-valine
• N-ALPHA-FMOC-D-VALINE
• N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-VALINE
• FLUORENYLMETHOXYCARBONYL-D-VALINE(FMOC-D-VAL-OH)
• 9-FLUORENYLMETHOXYCARBONYL-D-VALINE
• Nα-(9-Fluorenylmethyloxycarbonyl)-D-valine ,99%
• FMOC-D-VAL
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-VALINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-VALINE
• FMOC-D-VALINE
• N-FMOC-D-VALINE
• FMOC-D-VALINE extrapure
• FMOC-D-VALINE 98%
• N-(9-Fluorenylmethoxycarbonyl)-D-valine, Fmoc-D-valine
• N-9-FLUORENYLMETHYLOXYCARBONYL-D-VALINE

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine

CAS: 84624-17-9

Formula: C₂₀H₂₁NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 339.39

Ref: 3B-F0610

Fmoc-D-Val-OH

CAS: 84624-17-9

Bachem ID: 4007570.

Formula: C₂₀H₂₁NO₄

Purity: 99.9%

Color and Shape: White

Molecular weight: 339.39

Ref: 01-4007570

Fmoc-D-Val-OH

CAS: 84624-17-9

Formula: C₂₀H₂₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 339.3850

Ref: IN-DA003QN8

D-Valine, N-FMOC protected

CAS: 84624-17-9

D-Valine, N-FMOC protected

Purity: 98%

Color and Shape: White Powder

Molecular weight: 339.39g/mol

Ref: 54-OR52196

Fmoc-D-Val-OH

CAS: 84624-17-9

Formula: C₂₀H₂₁NO₄

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystalline powder

Molecular weight: 339.39

Ref: 7W-GM6407

Valine Impurity 2 (Fmoc-D-Val-OH)

CAS: 84624-17-9

Formula: C₂₀H₂₁NO₄

Molecular weight: 339.39

Ref: 4Z-V-047016

Fmoc-D-Val-OH

CAS: 84624-17-9

Fmoc-D-Val-OH is a synthetic acetal that is used as a substrate for protein modification. It has been shown to bind to the active site of enzymes such as butyrylcholinesterase and esterases, which are involved in the metabolism of fatty acids. Fmoc-D-Val-OH also binds to mammalian cells and can be conjugated with other molecules, such as nanoribbons, to improve their solubility in water.

Formula: C₂₀H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 339.39 g/mol

Ref: 3D-FF37758

Fmoc-D-Val-OH

CAS: 84624-17-9

M03380 - Fmoc-D-Val-OH

Formula: C₂₀H₂₁NO₄

Purity: 97%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 339.391

Ref: 10-M03380

FMOC-D-Valine extrapure, 99%

CAS: 84624-17-9

Formula: C₂₀H₂₁NO₄

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 339.40

Ref: SR-15917

N-Fmoc-D-valine

Controlled Product

CAS: 84624-17-9

Applications N-Fmoc-D-valine is an N-Fmoc-protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.
References Chu, W., et al.: J. Am. Chem. Soc., 116, 7971 (1994); Gilbert, S & Migeon, B.: J. Cell. Phys., 92, 161 (1977); Salzman, L., et al.: J. Biol. Chem., 239, 1864 (1964); Sordillo, L., et al.: Cell Biol. Int. Rep., 12, 355 (1988)

Formula: C₂₀H₂₁NO₄

Color and Shape: Neat

Molecular weight: 339.39

Ref: TR-F680005