CAS 84625-59-2

Dotarizine

Description:

Dotarizine is a chemical compound classified as a calcium channel blocker, primarily used in the treatment of various vascular disorders. It is known for its ability to inhibit calcium influx through voltage-gated calcium channels, which can lead to vasodilation and improved blood flow. The compound is often explored for its potential benefits in treating conditions such as migraine and peripheral vascular diseases. Dotarizine exhibits a relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Its molecular structure includes specific functional groups that contribute to its pharmacological activity. As with many medications, the efficacy and safety profile of Dotarizine is determined through clinical studies, and it may have side effects that need to be monitored. Overall, Dotarizine represents a significant area of interest in pharmacology, particularly in the context of managing circulatory and neurological conditions.

Formula: C₂₉H₃₄N₂O₂

InChI: InChI=1S/C29H34N2O2/c1-4-11-25(12-5-1)28(26-13-6-2-7-14-26)31-21-19-30(20-22-31)18-10-17-29(32-23-24-33-29)27-15-8-3-9-16-27/h1-9,11-16,28H,10,17-24H2

InChI key: InChIKey=LRMJAFKKJLRDLE-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)C4(OCCO4)C5=CC=CC=C5

Synonyms:

• 1-(Diphenylmethyl)-4-(3-(2-phenyl-1,3-dioxolan-2-yl)propyl)piperazine
• 1-Benzhydryl-4-(3-(2-phenyl-1,3-dioxolan-2-yl)propyl)piperazine
• Dotarizina
• Dotarizina [Spanish]
• Dotarizine [INN]
• Dotarizinum
• Dotarizinum [Latin]
• Piperazine, 1-(diphenylmethyl)-4-(3-(2-phenyl-1,3-dioxolan-2-yl)propyl)-
• Unii-Io7663S6D3
• Dotarizine

Dotarizine

Controlled Product

CAS: 84625-59-2

Formula: C₂₉H₃₄N₂O₂

Color and Shape: Neat

Molecular weight: 442.59

Ref: TR-D535750

Dotarizine

CAS: 84625-59-2

Dotarizine is a 5-HT2 receptor antagonist; active metabolite, FI 6020, detected by gas chromatography.

Formula: C₂₉H₃₄N₂O₂

Color and Shape: Solid

Molecular weight: 442.59

Ref: TM-T68580