CAS 84633-29-4

Eurycomanone

Description:

Eurycomanone is a natural compound primarily extracted from the roots of the Eurycoma longifolia plant, commonly known as Tongkat Ali. It is classified as a quassinoid, a type of compound known for its bitter taste and potential medicinal properties. Eurycomanone is recognized for its various biological activities, including potential aphrodisiac effects, anti-cancer properties, and the ability to enhance athletic performance by increasing testosterone levels. The compound has garnered interest in traditional medicine and dietary supplements, particularly in Southeast Asia. Its chemical structure features a complex arrangement of carbon rings, contributing to its unique properties. Eurycomanone is typically studied for its pharmacological effects, including its role in promoting male reproductive health and its potential to improve energy levels and overall vitality. As with many natural compounds, further research is ongoing to fully understand its mechanisms of action and therapeutic potential.

Formula: C₂₀H₂₄O₉

InChI: InChI=1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1

InChI key: InChIKey=UCUWZJWAQQRCOR-OKNZMGBLSA-N

SMILES: O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=CC(=O)[C@H]5O)[H])([C@@](O)(OC4)[C@H](O)C2=C)[H]

Synonyms:

• Pasakbumin A
• (1β,11β,12α,15β)-11,20-Epoxy-1,11,12,14,15-pentahydroxypicrasa-3,13(21)-diene-2,16-dione
• Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
• 2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran, picrasa-3,13(21)-diene-2,16-dione deriv.
• Eurycomanone

Eurycomanone

CAS: 84633-29-4

Formula: C₂₀H₂₄O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 408.3992

Ref: IN-DA00G59J

Eurycomanone

CAS: 84633-29-4

Formula: C₂₀H₂₄O₉

Molecular weight: 408.40

Ref: 7W-GY5621

EURYCOMANONE

CAS: 84633-29-4

EURYCOMANONE

Purity: ≥98%

Molecular weight: 408.4g/mol

Ref: 54-BUP03480

Eurycomanone

CAS: 84633-29-4

Eurycomanone has cytotoxic on HepG2 cells and Human Cervical Carcinoma Cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.[1,2]

Formula: C₂₀H₂₄O₉

Purity: 95%~99%

Color and Shape: Cryst.

Molecular weight: 408.403

Ref: BP-BP1784

EURYCOMANONE

CAS: 84633-29-4

Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.

Formula: C₂₀H₂₄O₉

Purity: 98.15% - 99.95%

Color and Shape: Solid

Molecular weight: 408.4

Ref: TM-T7027

Eurycomanone

CAS: 84633-29-4

Oxygen-heterocyclic compound

Formula: C₂₀H₂₄O₉

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 408.4

Ref: 5G-85739

Eurycomanone

Controlled Product

CAS: 84633-29-4

Applications Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
References Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);

Formula: C₂₀H₂₄O₉·2H₂O

Purity: >90%

Color and Shape: Neat

Molecular weight: 444.43

Ref: TR-E939010

Eurycomanone - Bio-X ™

CAS: 84633-29-4

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₀H₂₄O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 408.4 g/mol

Ref: 3D-BE300078

Eurycomanone

CAS: 84633-29-4

Eurycomanone is a natural product that belongs to the group of quassinoids. It is obtained from the plant Eurycoma longifolia, which grows in tropical Asia and Africa. The extract has been shown to have clinical properties such as body formation, protein target, and surface methodology. 3T3-L1 preadipocytes were used for the in vitro assays of eurycomanone. Group P2 cells were used for histological analysis and pharmacological agents were found to be chemical stable.

Formula: C₂₀H₂₄O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 408.4 g/mol

Ref: 3D-FE74396