CAS 84680-75-1

Astragaloside I

Description:

Astragaloside I is a natural compound primarily derived from the root of Astragalus membranaceus, a plant commonly used in traditional medicine. It belongs to the class of saponins, which are glycosides with a steroid or triterpenoid aglycone. Astragaloside I is known for its potential pharmacological properties, including immunomodulatory, antioxidant, and anti-inflammatory effects. The compound is characterized by its ability to enhance immune function and promote cellular health, making it of interest in both herbal medicine and modern pharmacology. It is typically studied for its role in protecting against oxidative stress and its potential benefits in various health conditions, including cardiovascular diseases and diabetes. Astragaloside I is soluble in water and organic solvents, which facilitates its extraction and use in various formulations. Its safety profile is generally considered favorable, although further research is necessary to fully understand its mechanisms of action and therapeutic potential.

Formula: C₄₃H₆₈O₁₆

InChI: InChI=1/C43H68O16/c1-20(45)54-33-25(48)18-53-37(34(33)55-21(2)46)56-22-8-11-42-19-43(42)13-12-39(5)35(41(7)10-9-29(59-41)38(3,4)52)24(47)16-40(39,6)28(43)15-26(23(42)14-22)57-36-32(51)31(50)30(49)27(17-44)58-36/h22-37,44,47-52H,8-19H2,1-7H3/t22-,23?,24-,25+,26-,27+,28-,29-,30+,31-,32+,33-,34+,35-,36+,37-,39+,40-,41+,42+,43+/m0/s1

InChI key: InChIKey=KXHCYYSIAXMSPA-OOCCOBHWSA-N

SMILES: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]

Synonyms:

• (3β,6α,16β,20R,24S)-3-[(2,3-Di-O-acetyl-β-<span class="text-smallcaps">D</smallcap>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Anemarsaponin E
• Astrasieversianin IV
• Cyclosieversioside B
• astragalosideⅠ
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2,3-di-O-acetyl-β-<smallcap>D</span>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-D-glucopyranoside deriv.
• 9,19-Cyclolanostane, β-D-glucopyranoside deriv.
• Astragaloside I
• (3β,6α,16β,20R,24S)-3-[(2,3-Di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2,3-di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragaloside I (Astrasieversianin IV
• Astragaloside I 84680-75-1
• Astragaloside l, 98%, from Astragalus membranaceus Bunge
• 20,24-EPOXYCYCLOARTANE-3,16,25-TRIOL-6-O-BETA-D-GLUCOPYRANOSIDE
• Cyclosiversioside B
• ASTRAGALOSIDE I USP/EP/BP
• ASTRAGALOSIDE I(SH)

β-​D-​Glucopyranoside, (3β,​6α,​16β,​20R,​24S)​-​3-​[(2,​3-​di-​O-​acetyl-​β-​D-​xylopyranosyl)​oxy]​-​20,​24-​epoxy-​16,​25-​dihydroxy-​9,​19-​cyclolanostan-​6-​yl

CAS: 84680-75-1

Formula: C₄₅H₇₂O₁₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 869.0436

Ref: IN-DA00G3A7

Astragaloside I

CAS: 84680-75-1

Astragaloside I

Purity: ≥98%

Molecular weight: 869.04g/mol

Ref: 54-BUP10701

Astragaloside I

CAS: 84680-75-1

Formula: C₄₅H₇₂O₁₆

Molecular weight: 869.04

Ref: 7W-GC4970

Astragaloside I

CAS: 84680-75-1

AstragalosideΙ(As-Ι), one of the main active ingredients in Astragalus membranaceus, As-I stimulates osteoblast differentiation through the Wnt/β-catenin signaling pathway, which also activates the BMP pathway and RANK pathway, thus highlighting the As-Ιfor pharmaceutical and medicinal applications such as treating bone disease.

Formula: C₄₅H₇₂O₁₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 869.055

Ref: BP-BP0210

Astragaloside I

CAS: 84680-75-1

Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus.

Formula: C₄₅H₇₂O₁₆

Purity: 98.9% - 99.64%

Color and Shape: White Crystal

Molecular weight: 869.04

Ref: TM-T3925

Astragaloside i

CAS: 84680-75-1

Natural glycoside

Formula: C₄₅H₇₂O₁₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 869.06

Ref: 5G-89572

Astragaloside I

Controlled Product

CAS: 84680-75-1

Applications Astragaloside I has cardioprotective effects as well as causing improvement in cognitive function.
References Zhang, Q. et al.: Chin. Med. J., 126, 1551 (2013); Ye, G. et al.: Biomed. Chrom., 24, 1147 (2010);

Formula: C₄₅H₇₂O₁₆

Color and Shape: Neat

Molecular weight: 869.04

Ref: TR-A790145

Astragaloside I

CAS: 84680-75-1

Astragaloside I is a bioactive saponin, which is a naturally occurring chemical compound found primarily in the roots of Astragalus membranaceus, a traditional Chinese medicinal herb. This compound acts by interacting with various cellular and molecular pathways, demonstrating antioxidant, anti-inflammatory, and anti-apoptotic properties. Through these mechanisms, astragaloside I influences cell signaling and modulates the expression of genes associated with stress responses and metabolic processes.

Formula: C₄₅H₇₂O₁₆

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 869.04 g/mol

Ref: 3D-MA10037