CymitQuimica logo

CAS 84693-92-5

:

(16beta,17beta)-16-fluoroestra-1,3,5(10)-triene-3,17-diol

Description:
The chemical substance known as (16beta,17beta)-16-fluoroestra-1,3,5(10)-triene-3,17-diol, with the CAS number 84693-92-5, is a synthetic steroid that belongs to the class of estrogens. It features a fluorine atom at the 16th carbon position, which modifies its biological activity compared to natural estrogens. This compound has a triene structure, indicating the presence of three conjugated double bonds, which contributes to its stability and reactivity. The hydroxyl groups at the 3 and 17 positions enhance its solubility in water and its interaction with estrogen receptors. As a selective estrogen receptor modulator (SERM), it may exhibit tissue-selective estrogenic or anti-estrogenic effects, making it of interest in therapeutic applications, particularly in hormone-related conditions. Its unique structural characteristics influence its pharmacokinetics, potency, and potential side effects. Due to its specific modifications, this compound is studied for its potential in hormone replacement therapy and cancer treatment, particularly in estrogen-sensitive tissues.
Formula:C18H23FO2
InChI:InChI=1/C18H23FO2/c1-18-7-6-13-12-5-3-11(20)8-10(12)2-4-14(13)15(18)9-16(19)17(18)21/h3,5,8,13-17,20-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,17+,18+/m1/s1
Synonyms:
  • Estra-1,3,5(10)-triene-3,17-diol, 16-fluoro-, (16beta,17beta)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
  • 16-Fluoroestradiol
    Biosynth
    + Info

    16-Fluoroestradiol

    Controlled Product
    CAS:
    <p>16-Fluoroestradiol is a fluorinated form of estradiol that binds to the estrogen receptor. It has been shown to have high affinity for the receptor and is found in tissues such as breast, uterus, and vagina. 16-Fluoroestradiol has been used in cancer research to study uptake and metabolism of estrogens. The drug is metabolized by hydroxylation via cytochrome P450 enzymes and through the action of nucleophilic enzymes such as carboxylesterases. 16-Fluoroestradiol has also been shown to bind to muscle tissue, which may be due to its ability to inhibit uptake of glucose into cells.</p>
    Formula:C18H23FO2
    Purity:Min. 95%
    Molecular weight:290.37 g/mol

    Ref: 3D-FF77214

    ne
    To inquire