CAS 847-86-9

4-Hydroxy-3-methoxy-17-methylmorphinan-6-one

Description:

4-Hydroxy-3-methoxy-17-methylmorphinan-6-one, commonly known as morphine derivative, is a semi-synthetic opioid with notable analgesic properties. This compound is characterized by its complex morphinan structure, which includes a hydroxyl group at the 4-position and a methoxy group at the 3-position, contributing to its pharmacological activity. The presence of a ketone at the 6-position and a methyl group at the 17-position further defines its chemical identity. It exhibits a high affinity for opioid receptors, particularly the mu-opioid receptor, which is responsible for its pain-relieving effects. The compound is typically administered in controlled settings due to its potential for addiction and side effects, including respiratory depression and sedation. Its solubility in organic solvents and limited solubility in water are important for formulation considerations in pharmaceutical applications. Overall, 4-Hydroxy-3-methoxy-17-methylmorphinan-6-one is significant in medicinal chemistry, particularly in the development of analgesics and understanding opioid receptor interactions.

Formula: C₁₈H₂₃NO₃

InChI: InChI=1/C18H23NO3/c1-19-8-7-18-10-12(20)4-5-13(18)14(19)9-11-3-6-15(22-2)17(21)16(11)18/h3,6,13-14,21H,4-5,7-10H2,1-2H3/t13-,14-,18+/m0/s1

InChI key: InChIKey=CDGFTOARGCEWKI-IYOUNJFTSA-N

SMILES: OC1=C2[C@@]34[C@]([C@@](CC2=CC=C1OC)(N(C)CC3)[H])(CCC(=O)C4)[H]

Synonyms:

• 2H-10,4a-Iminoethanophenanthren-3(4H)-one, 1,9,10,10a-tetrahydro-5-hydroxy-6-methoxy-11-methyl-
• 4-Hydroxy-3-methoxy-N-methyl-6-oxomorphinan
• 7,8-Dihydrothebainone
• 7,8-Dihydrothebainone A
• Dihydrothebainone
• Dihydrothebainone A
• Dihydrothobainone
• Morphinan, 4-hydroxy-3-methoxy-N-methyl-6-oxo-
• Morphinan-6-one, 4-hydroxy-3-methoxy-17-methyl-
• Nsc 134598
• Nsc 35545
• Ram-345
• Thebainone, dihydro-
• 4-Hydroxy-3-methoxy-17-methylmorphinan-6-one
• 4-Hydroxy-3-methoxy-17-methylmorphinan-6-one
• Hydrocodone Related CoMpound A CII
• 4-hydroxy-3-methoxy-n-methyl-6-oxo-morphina
• 4-hydroxy-3-methoxy-17-methyl-morphinan-6-on
• 3-Methoxy-4-hydroxy-6-oxo-17-methylmorphinan
• 1,9,10,10a-Tetrahydro-5-hydroxy-6-Methoxy-11-Methyl-2H-10,4a-iMinoethanophenanthren-3(4H)-one
• HYDROCODONE BITARTRATE RELATED COMPOUND A CII (70 MG) (MORPHINAN-6-ONE, 4-HYDROXY-3-METHOXY-17-METHYL)
• Hydrocodone Related Compound A CII (70 mg) (4-hydroxy-3-methoxy-17-methylmorphinan-6-one) (1315012)
• Hydrocodone Bitartrate Related Compound A CII (70 mg) (Morphinan-6-one, 4-hydroxy-3-methoxy-17-methyl)
• Oxycodone Hydrochloride Impurity 10

(-)-Dihydrothebainone

Controlled Product

CAS: 847-86-9

Formula: C₁₈H₂₃NO₃

Color and Shape: Neat

Molecular weight: 301.38

Ref: TR-D449820

Hydrocodone

Controlled Product

CAS: 847-86-9

Hydrocodone is a narcotic analgesic that binds to opioid receptors in the body. It is a semi-synthetic opioid derived from codeine, which is obtained from the opium poppy. Hydrocodone has been shown to have higher affinity for mu-opioid receptors than other opioids such as morphine, and it also has less affinity for kappa- and delta-receptors. Hydrocodone has a concentration–time curve that can be described by three phases: an initial rapid elimination phase, followed by a slower elimination phase with a plateau effect, and finally an elimination phase with decreasing concentrations. Hydrocodone may interact with nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen, since NSAIDs inhibit the enzyme cyclooxygenase 1 (COX1), which is responsible for conversion of arachidonic acid to prostaglandins that produce pain and inflammation. Hydrocodone may also interact

Formula: C₁₈H₂₃NO₃

Purity: Min. 95%

Molecular weight: 301.4 g/mol

Ref: 3D-AAA84786

Hydrocodone Related Compound A CII (4-hydroxy-3-methoxy-17-methylmorphinan-6-one)

Controlled Product

CAS: 847-86-9

Alkaloids of opium and their derivatives, salts thereof

Formula: C₁₈H₂₃NO₃

Color and Shape: White Powder

Molecular weight: 301.16779

Ref: 45-1315012