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CAS 847649-68-7

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8-Bromo-3'-deoxyguanosine

Description:
8-Bromo-3'-deoxyguanosine is a synthetic nucleoside analog of guanosine, characterized by the presence of a bromine atom at the 8-position of the purine base and a deoxyribose sugar moiety. This compound is often used in biochemical and molecular biology research, particularly in studies involving DNA synthesis and modification, as it can incorporate into DNA strands during replication. Its structure allows it to mimic natural nucleosides, which can lead to interesting effects on DNA stability and function. The bromine substitution can also influence the compound's reactivity and interactions with other biomolecules. 8-Bromo-3'-deoxyguanosine is known to exhibit properties that can induce mutagenesis, making it a valuable tool for studying DNA repair mechanisms and the effects of halogenated nucleosides on genetic material. Additionally, it is important to handle this compound with care due to its potential biological effects and the need for appropriate safety measures in laboratory settings.
Formula:C10H12BrN5O4
Synonyms:
  • 8-Bromo-3’-deoxyguanosine
  • 8-Bromo-3'-deoxyguanosine
  • Guanosine, 8-?bromo-?3'-?deoxy- (9CI)
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