CAS 847926-88-9

(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

Controlled Product

CAS: 847926-88-9

Applications (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one a building block for γ-secretase inhibitors for treatment of Alzheimer's disease (1,2). Several γ-secretase inhibitors have been described that contain this compound.
References (1) Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005) (2) Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2007)

Formula: C₁₄H₁₂N₂O

Color and Shape: Neat

Molecular weight: 224.26

Ref: TR-A604380

(S)-7-Amino-5H,7H-dibenzo[B,D]azepin-6-one

CAS: 847926-88-9

7-Amino-5H,7H-dibenzo[b,D]azepin-6-one is an enantiomer of 7-amino-5H,7H-dibenzo[b,d]azepin-6(10H)one. It is a chiral organic compound that can be synthesized by the epimerization of 2-(2′hydroxyphenyl)ethanol with sodium methoxide in methanol. This compound can also be synthesized by a sequence of reactions including racemization and enantioselective synthesis.

Formula: C₁₄H₁₂N₂O

Purity: Min. 95%

Molecular weight: 224.26 g/mol

Ref: 3D-XIB92688