CAS 84793-07-7

Fmoc-Glu-OtBu

Description:

Fmoc-Glu-OtBu, or 9-fluorenylmethoxycarbonyl-L-glutamic acid tert-butyl ester, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective deprotection during peptide assembly. The glutamic acid component contributes a carboxylic acid side chain, which can participate in various chemical reactions, while the tert-butyl ester (OtBu) protects the carboxylic acid group, enhancing the stability and solubility of the compound. Fmoc-Glu-OtBu is typically utilized in solid-phase peptide synthesis due to its compatibility with various coupling reagents and its ability to facilitate the formation of peptide bonds. The compound is generally stable under standard laboratory conditions but may require specific conditions for deprotection and coupling. Its structural features make it a valuable intermediate in the synthesis of peptides, particularly those requiring precise control over functional groups.

Formula: C₂₄H₂₇NO₆

Synonyms:

• Fmoc-L-Glutamic acid α-tert.butyl ester
• Fmoc-L-Glutamic acid 1-tert-butyl ester
• FMOC-GLU-OBUT
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMIC ACID ALPHA-T-BUTYL ESTER
• N-ALPHA-FMOC-L-GLUTAMIC ACID ALPHA-TERT-BUTYL ESTER
• FMOC-L-GLU-OTBU
• N-α-Fmoc-L-glutamic acid α-tert butyl ester
• N-FMOC-L-GLUTAMIC ACID-1-T-BUTYL ESTER
• L-GLUTAMIC ACID, N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-, 1-(1,1-DIMETHYLETHYL) ESTER
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID-T-BUTYL ESTER
• N-ALPHA-FMOC-L-GLUTAMIC ACID ALPHA-T-BUTYL ESTER
• FMOC-GLUTAMIC ACID-OTBU
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID ALPHA T-BUTYL ESTER
• FMOC-L-GLUTAMIC ACID ALPHA-T-BUTYL ESTER
• FMOC-L-GLUTAMIC ACID-A-T-BUTYLESTER

Fmoc-Glu-OtBu

CAS: 84793-07-7

Formula: C₂₄H₂₇NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 425.48

Ref: 3B-F1318

N-Fmoc-L-glutamic acid 1-tert-butyl ester, 98%

CAS: 84793-07-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₄H₂₇NO₆

Purity: 98%

Molecular weight: 425.48

Ref: 02-H62146

Fmoc-Glu-OtBu

CAS: 84793-07-7

Bachem ID: 4011877.

Formula: C₂₄H₂₇NO₆

Purity: 99.8%

Color and Shape: White

Molecular weight: 425.48

Ref: 01-4011877

Fmoc-L-Glutamic Acid 1-Tert-Butyl Ester

CAS: 84793-07-7

Formula: C₂₄H₂₇NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 425.4743

Ref: IN-DA0034Y1

Fmoc-Glu-OtBu

CAS: 84793-07-7

Formula: C₂₄H₂₇NO₆

Purity: ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 425.47

Ref: 7W-GZ0287

Fmoc-Glu-OtBu

CAS: 84793-07-7

Fmoc-Glu-OtBu

Formula: C₂₄H₂₇NO₆

Purity: 98%

Color and Shape: white powder

Molecular weight: 425.47g/mol

Ref: 54-OR52597

Fmoc-L-Glu-OtBu

CAS: 84793-07-7

Fmoc-L-Glu-OtBu is a synthetic ligand that is used as a fluorescent probe in vivo. It has been shown to bind to semaglutide with high affinity, and it can be used to study the function of semaglutide in the cell. Fmoc-L-Glu-OtBu has also been found to have an inhibitory effect on cancer cells. This ligand can be synthesized by solid-phase synthesis and purified by column chromatography. The purity of Fmoc-L-Glu-OtBu is confirmed by elemental analysis, and its impurities are determined by fluorescence spectroscopy. The carboxylate group of Fmoc-L-Glu-OtBu is activated with sulfuric acid to form the corresponding active ester, which can then be conjugated with other molecules.

Formula: C₂₄H₂₇NO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 425.47 g/mol

Ref: 3D-FF15874

fmoc-glu-otbu

CAS: 84793-07-7

Formula: C₂₄H₂₇NO₆

Purity: 97%

Color and Shape: Solid, Powder

Molecular weight: 425.481

Ref: 10-F045463