CAS 84806-27-9

7-Fluorobenzofurazan-4-sulfonic acid ammonium salt

Description:

7-Fluorobenzofurazan-4-sulfonic acid ammonium salt is a chemical compound characterized by its unique structure, which includes a benzofurazan moiety substituted with a fluorine atom and a sulfonic acid group. This compound is typically used in various chemical applications, including as a reagent in organic synthesis and in the development of fluorescent probes. The presence of the sulfonic acid group enhances its solubility in water, making it suitable for use in aqueous environments. The ammonium salt form indicates that the sulfonic acid has been neutralized with ammonium, which can influence its reactivity and solubility properties. Additionally, the fluorine atom can impart specific electronic and steric effects, potentially affecting the compound's reactivity and interaction with biological systems. Overall, this compound is of interest in both synthetic chemistry and potential applications in biochemistry due to its distinctive functional groups and properties.

Formula: C₆H₆FN₃O₄S

InChI: InChI=1/C6H3FN2O4S.H3N/c7-3-1-2-4(14(10,11)12)6-5(3)8-13-9-6;/h1-2H,(H,10,11,12);1H3

SMILES: c1cc(c2c(c1F)non2)S(=O)(=O)O.N

Synonyms:

• 7-Fluorobenzofurazane-4-Sulfonic Acid Ammonium Salt
• 7-Fluorobenzo-2-Oxa-1,3-Diazole-4-*Sulfonic Acid
• 7-Fluoro-2,1,3-Benzoxadiazole-4-Sulfonic Acid Ammoniate (1:1)

7-Fluorobenzofurazan-4-sulfonic acid ammonium salt, 99%

CAS: 84806-27-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₆FN₃O₄S

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to yellow to pale orange

Molecular weight: 235.19

Ref: 02-B21767

Ammonium 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate

CAS: 84806-27-9

Formula: C₆H₆FN₃O₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 235.1929

Ref: IN-DA003NFB

Ammonium 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate

CAS: 84806-27-9

Formula: C₆H₆FN₃O₄S

Purity: (HPLC) ≥ 98.0%

Color and Shape: Yellow powder

Molecular weight: 235.19

Ref: 7W-GT7479

Ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulphonate

CAS: 84806-27-9

Ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulphonate

Formula: C₆H₂FN₂O₄S·H₄N

Purity: ≥95%

Color and Shape: golden yellow solid

Molecular weight: 235.19g/mol

Ref: 54-PC8115

Ammonium 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate

Controlled Product

CAS: 84806-27-9

Stability Light Sensitive, Hygroscopic
Applications A water soluble bifunctional fluorogenic reagent for the sensitive and specific detection of thiols in biological specimens or proteins.SBD-F has high reactivity to thiol compounds to attain low detection limits; no flourescence in itself; biological buffer solublility; stability at RT in water for >1 week. The optimal condition for reaction was 60oC and pH 9.5 for 1 h.Please refer to the following references for more specific information regarding the application of SBD-F as a fluorogenic reagent for detection of cysteine containing peptides.Fluorescence: max Abs. l = 380 nm, max Em. l = 515 nm; Molar Abs. > 4x103 (ca. 317nm)
References Imai, K., et al.: Anal. Biochem., 128, 471 (1983); Sueyoshi, T., et al.: J. Biochem., 97, 1811 (1985), Lagana, A., et al.: Anal. Biochem., 215, 266 (1993); Singh, B.K., et al.: J. Liq. Chromatogr., 17, 4469 (1994); Bishop, A.P., et al.: Free Radical Biol. Med., 18, 617 (1995);

Formula: C₆H₃FN₂O₄S·H₃N

Color and Shape: Neat

Molecular weight: 235.19

Ref: TR-A634000

7-Fluorobenzo-2-oxa-1,3-diazole-4-sulfonic acid ammonium

CAS: 84806-27-9

7-Fluorobenzo-2-oxa-1,3-diazole-4-sulfonic acid ammonium is a fluorescent derivative that is used in clinical pathology to study human metabolism. The compound reacts with blood cells to form a fluorescent derivative that can be detected by use of a fluorescence detector. A sample preparation technique is required to prepare the blood samples before analysis. 7-Fluorobenzo-2-oxa-1,3-diazole-4-sulfonic acid ammonium has been shown to react with disulfide bonds and endogenous substances, such as glutathione, dopamine and serotonin. The detection sensitivity for this compound is approximately 10 pM.

Formula: C₆H₆FN₃O₄S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 235.19 g/mol

Ref: 3D-FF96629

7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)

CAS: 84806-27-9

7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emission maxima of 380/515 nm, respectively.1 1.Imai, K., Toyo'oka, T., and Watanabe, Y.A novel fluorogenic reagent for thiols: Ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonateAnal. Biochem.128(2)471-473(1983) 2.Ichinose, S., Nakamura, M., Maeda, M., et al.A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasmaBiomed. Chromatogr.23(9)935-939(2009)

Formula: C₆H₆FN₃O₄S

Color and Shape: Solid

Molecular weight: 235.19

Ref: TM-T37002