CAS 848139-78-6

6-Amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-3-quinolinecarbonitrile

Description:

6-Amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-3-quinolinecarbonitrile is a synthetic organic compound characterized by its complex structure, which includes a quinoline core, amino groups, and a chloro-substituted phenyl moiety. This compound features a carbonitrile functional group, contributing to its potential reactivity and biological activity. The presence of the ethoxy group enhances its solubility in organic solvents, while the pyridinylmethoxy group may influence its interaction with biological targets, potentially making it a candidate for pharmaceutical applications. The chlorine atom in the structure can also affect the compound's electronic properties and lipophilicity. Overall, this compound's unique arrangement of functional groups suggests it may exhibit interesting pharmacological properties, warranting further investigation in medicinal chemistry and drug development contexts. Its CAS number, 848139-78-6, serves as a unique identifier for regulatory and research purposes, facilitating its study in various scientific disciplines.

Formula: C₂₄H₂₀ClN₅O₂

InChI: InChI=1S/C24H20ClN5O2/c1-2-31-23-11-21-18(10-20(23)27)24(15(12-26)13-29-21)30-16-6-7-22(19(25)9-16)32-14-17-5-3-4-8-28-17/h3-11,13H,2,14,27H2,1H3,(H,29,30)

InChI key: InChIKey=WRGKROVGVSWJMI-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(OCC)C(N)=C2)N=CC1C#N)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3

Synonyms:

• 3-Quinolinecarbonitrile, 6-amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-
• 4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline
• 6-Amino-4-(3-Chloro-4-((2-Pyridinyl)Methoxy)Anilino)-3-Cyano-7-Ethoxyquinoline
• 6-Amino-4-(3-Chloro-4-(Pyridin-2-Ylmethoxy)Phenylamino)-7-Ethoxyquinoline-3-Carbonitrile
• 6-Amino-4-[[3-Chloro-4-(2-Pyridinylmethoxy)Phenyl]Amino]-7-Ethoxy-3-Quinolinecarbonitrile

3-Quinolinecarbonitrile,6-amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-

CAS: 848139-78-6

Formula: C₂₄H₂₀ClN₅O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 445.9009

Ref: IN-DA00IDG1

6-Amino-4-((3-Chloro-4-(Pyridin-2-Ylmethoxy)Phenyl)Amino)-7-Ethoxyquinoline-3-Carbonitrile

CAS: 848139-78-6

6-Amino-4-((3-Chloro-4-(Pyridin-2-Ylmethoxy)Phenyl)Amino)-7-Ethoxyquinoline-3-Carbonitrile

Purity: 99%

Molecular weight: 445.90g/mol

Ref: 54-OR1011979

Neratinib Impurity 15

CAS: 848139-78-6

Formula: C₂₄H₂₀ClN₅O₂

Molecular weight: 445.91

Ref: 4Z-N-088024

6-Amino-4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-7-ethoxyquinoline-3-carbonitrile

CAS: 848139-78-6

Purity: 98%

Molecular weight: 445.9100036621094

Ref: 10-F788588

Des-(4-(dimethylamino)-2-butenoyl)-Neratinib

Controlled Product

CAS: 848139-78-6

Applications 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.
References Carmi, C., et al.: J. Med. Chem., 55, 2251 (2012)

Formula: C₂₄H₂₀ClN₅O₂

Color and Shape: Neat

Molecular weight: 445.9

Ref: TR-A604050

Neratinib Impurity 2

CAS: 848139-78-6

Formula: C₂₄H₂₀ClN₅O₂

Molecular weight: 445.91

Ref: ST-EA-CP-N31004