CAS 848259-27-8

Pemafibrate

Description:

Pemafibrate, with the CAS number 848259-27-8, is a novel medication primarily classified as a selective peroxisome proliferator-activated receptor alpha (PPARα) modulator. It is designed to improve lipid profiles by effectively lowering triglyceride levels and increasing high-density lipoprotein (HDL) cholesterol. Pemafibrate exhibits a high affinity for PPARα, which plays a crucial role in lipid metabolism and inflammation regulation. The substance is characterized by its relatively low molecular weight and specific structural features that enhance its pharmacological activity. It is typically administered orally and has been studied for its potential benefits in managing dyslipidemia and reducing cardiovascular risk. Pemafibrate is notable for its favorable safety profile and minimal side effects compared to traditional fibrates, making it a promising option for patients with metabolic disorders. Its mechanism of action involves the modulation of genes involved in fatty acid oxidation and lipoprotein metabolism, contributing to its therapeutic effects in lipid regulation.

Formula: C₂₈H₃₀N₂O₆

InChI: InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1

InChI key: InChIKey=ZHKNLJLMDFQVHJ-RUZDIDTESA-N

SMILES: N(CC1=CC(O[C@@H](C(O)=O)CC)=CC=C1)(CCCOC2=CC=C(OC)C=C2)C3=NC=4C(O3)=CC=CC4

Synonyms:

• (R)-K 13675
• Pemafibrate
• Butanoic acid, 2-[3-[[2-benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]-, (2R)-
• (2R)-2-[3-[[2-Benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
• (R)-2-[3-[[N-(Benzoxazol-2-yl)-N-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid

Pemafibrate

CAS: 848259-27-8

Formula: C₂₈H₃₀N₂O₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 490.5476

Ref: IN-DA00G7DN

(R)-2-(3-((Benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid

CAS: 848259-27-8

(R)-2-(3-((Benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid

Purity: 99%

Molecular weight: 490.56g/mol

Ref: 54-OR1074814

Pemafibrate

CAS: 848259-27-8

Formula: C₂₈H₃₀N₂O₆

Molecular weight: 490.56

Ref: 4Z-P-428001

Pemafibrate-13C-d3

CAS: 848259-27-8

Formula: C₂₇₁₃CH₂₇D₃N₂O₆

Molecular weight: 494.57

Ref: 4Z-P-428002

Pemafibrate

CAS: 848259-27-8

Pemafibrate is a research chemical that has shown potential in various applications. It is derived from d-tagatose and has been studied for its emissions-reducing properties. Pemafibrate also exhibits properties similar to dianhydrogalactitol, an aluminum-based compound used in certain industrial processes. Additionally, it has been explored as a nitrification inhibitor, which can help reduce the release of metallic compounds into the environment.

Formula: C₂₈H₃₀N₂O₆

Purity: Min. 95%

Molecular weight: 490.55 g/mol

Ref: 3D-YIB25927