CAS 848318-25-2

SSR128129E

Description:

SSR128129E, with the CAS number 848318-25-2, is a selective serotonin receptor modulator that primarily targets the serotonin 5-HT2C receptor. This compound is known for its potential applications in the treatment of various psychiatric disorders, including depression and anxiety, due to its ability to enhance serotonergic neurotransmission. SSR128129E exhibits high selectivity for the 5-HT2C receptor over other serotonin receptors, which may contribute to its therapeutic profile and reduced side effects compared to non-selective agents. The compound is typically characterized by its chemical structure, which includes specific functional groups that facilitate its interaction with the receptor. Additionally, SSR128129E has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are crucial for understanding its efficacy and safety in clinical settings. As research continues, SSR128129E may provide insights into novel treatment strategies for mood disorders, highlighting the importance of selective receptor modulation in pharmacotherapy.

FGFR inhibitor

CAS: 848318-25-2

Formula: C₁₈H₁₅N₂NaO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 346.3125

Ref: IN-DA00G3PX

Sodium 2-Amino-5-(1-Methoxy-2-Methylindolizine-3-Carbonyl)Benzoate

CAS: 848318-25-2

Sodium 2-Amino-5-(1-Methoxy-2-Methylindolizine-3-Carbonyl)Benzoate

Purity: 98%

Molecular weight: 346.31g/mol

Ref: 54-OR1023158

SSR128129E

CAS: 848318-25-2

SSR128129E

Purity: ≥95%

Molecular weight: 346.31g/mol

Ref: 54-BUP10027

SSR128129E

CAS: 848318-25-2

SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.

Formula: C₁₈H₁₅N₂O₄·Na

Purity: 98.79% - ≥95%

Color and Shape: Solid

Molecular weight: 346.31

Ref: TM-T6082

SSR128129E

CAS: 848318-25-2

Purity: 95.0%

Molecular weight: 346.318

Ref: 10-F468370

SSR128129E

Controlled Product

CAS: 848318-25-2

Applications SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR). Oral delivery of SSR128129E inhibits arthritis and tumors that are relatively refractory to anti-vascular endothelial growth factor receptor-2 antibodies.
References Bono, F., et al.: Cancer Cell., 23, 477 (2013); Dol-Gleizes, F., et al.: PLoS One, 8, e80027 (2013)

Formula: C₁₈H₁₅N₂NaO₄

Color and Shape: Yellowish Solid

Molecular weight: 346.31

Ref: TR-S684470