CAS 84845-75-0

Niperotidine

Description:

Niperotidine is a chemical compound classified as a histamine H2 receptor antagonist, primarily used in the treatment of conditions such as peptic ulcers and gastroesophageal reflux disease (GERD). It works by inhibiting the action of histamine on H2 receptors in the stomach lining, thereby reducing gastric acid secretion. Niperotidine is characterized by its relatively high potency and selectivity for H2 receptors, which contributes to its therapeutic efficacy. The compound typically appears as a white to off-white crystalline powder and is soluble in water and various organic solvents. Its molecular structure includes a pyridine ring, which is common among H2 antagonists, and it exhibits a favorable pharmacokinetic profile, allowing for effective absorption and distribution in the body. As with many pharmaceuticals, potential side effects may include gastrointestinal disturbances and central nervous system effects, although these are generally mild. Overall, Niperotidine represents a significant advancement in the management of acid-related disorders.

Formula: C₂₀H₂₆N₄O₅S

InChI: InChI=1S/C20H26N4O5S/c1-23(2)11-16-4-5-17(29-16)13-30-8-7-21-20(12-24(25)26)22-10-15-3-6-18-19(9-15)28-14-27-18/h3-6,9,12,21-22H,7-8,10-11,13-14H2,1-2H3

InChI key: InChIKey=HXRSXEDVVARPHP-UHFFFAOYSA-N

SMILES: C(NC(NCCSCC=1OC(CN(C)C)=CC1)=CN(=O)=O)C=2C=C3C(=CC2)OCO3

Synonyms:

• 1,1-Ethenediamine, N-(1,3-benzodioxol-5-ylmethyl)-N'-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-2-nitro-
• N-(1,3-Benzodioxol-5-ylmethyl)-N'-(2-((5-((dimethylamino)methyl)furfuryl)thio)ethyl)-2-nitrovinylidenediamine
• N-(1,3-Benzodioxol-5-ylmethyl)-N′-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitro-1,1-ethenediamine
• N-(1,3-benzodioxol-5-ylmethyl)-N'-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-2-nitroethane-1,1-diamine
• N-(2-((5-((Dimethylamino)methyl)furfuryl)thio)ethyl)-2-nitro-N'-piperonyl-1,1-ethenediamine
• Niperotidina
• Niperotidina [Spanish]
• Niperotidine [INN]
• Niperotidinum
• Niperotidinum [Latin]
• Piperonyl-ranitidine
• Unii-12Jbd7U72K

N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethyl]-2-nitrovinylidenediamine

CAS: 84845-75-0

Formula: C₂₀H₂₆N₄O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 434.5092

Ref: IN-DA00G58R

Niperoditine

Controlled Product

CAS: 84845-75-0

Stability Hygroscopic
Applications Niperoditine is a H2 antagonists used in the treatment intestinal disorders.
References Mannino, S. et al.: Pharmacoepidemiol. Drug Safety, 7, 233 (1998); Miyaji, Y. et al.: Bioanalysis., 4, 263 (2012);

Formula: C₂₀H₂₆N₄O₅S

Color and Shape: Neat

Molecular weight: 434.51

Ref: TR-N478800

Niperotidine

CAS: 84845-75-0

Histamine H2-receptor antagonist

Formula: C₂₀H₂₆N₄O₅S

Purity: Min. 95%

Molecular weight: 434.51 g/mol

Ref: 3D-BN174859

Niperotidine

CAS: 84845-75-0

Niperotidine is an antagonist of histamine H2-receptor.

Formula: C₂₀H₂₆N₄O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 434.51

Ref: TM-T12228