CAS 848469-29-4

3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(3-chloro-1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride

Description:

3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(3-chloro-1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride is a complex organic compound characterized by its multi-functional structure, which includes a pyrimidine ring, a triazole moiety, and a butanol derivative. The presence of chlorine and fluorine substituents contributes to its unique chemical properties, potentially enhancing its biological activity and solubility. This compound is typically utilized in pharmaceutical research, particularly in the development of antiviral or antifungal agents, due to its ability to interact with specific biological targets. The hydrochloride salt form indicates improved stability and solubility in aqueous environments, which is advantageous for formulation and delivery in medicinal applications. Its synthesis involves multiple steps, including the introduction of various functional groups, and requires careful handling due to the presence of halogens, which can influence reactivity and toxicity. Overall, this compound exemplifies the intricate design often found in modern medicinal chemistry aimed at optimizing therapeutic efficacy.

Formula: C₁₆H₁₃Cl₃F₃N₅O

InChI: InChI=1/C16H12Cl2F3N5O.ClH/c1-8(13-12(21)14(17)23-6-22-13)16(27,5-26-7-24-15(18)25-26)10-3-2-9(19)4-11(10)20;/h2-4,6-8,27H,5H2,1H3;1H/t8-,16+;/m0./s1

Synonyms:

• (2R,3S)-3-(6-Chloro-5-fluoropyrimidin-4-yl)-1-(3-chloro-1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride (1:1)
• 4-pyrimidineethanol, 6-chloro-α-[(3-chloro-1H-1,2,4-triazol-1-yl)methyl]-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-, (alphaR,betaS)-, hydrochloride (1:1)
• 3-(6-Chloro-5-Fluoropyrimidin-4-Yl)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-Triazol-1-Yl)Butan-2-Ol