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CAS 84880-03-5

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Cefpimizole

Description:
Cefpimizole is a synthetic antibiotic belonging to the class of cephalosporins, which are characterized by their beta-lactam structure. It is primarily used for its antibacterial properties, effective against a range of Gram-positive and Gram-negative bacteria. Cefpimizole works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection and is known for its stability against certain beta-lactamases, which are enzymes produced by some bacteria to resist antibiotic action. Its pharmacokinetics include good tissue penetration and a relatively short half-life, necessitating multiple doses for effective treatment. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential impacts on renal function. As with other antibiotics, the emergence of resistance is a concern, highlighting the importance of appropriate use in clinical settings. Overall, cefpimizole represents a valuable option in the arsenal against bacterial infections, particularly in cases where other antibiotics may be ineffective.
Formula:C28H26N6O10S2
InChI:InChI=1S/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1
InChI key:InChIKey=LNZMRLHZGOBKAN-KAWPREARSA-N
SMILES:C([O-])(=O)C=1N2[C@@]([C@H](NC([C@H](NC(=O)C3=C(C(O)=O)N=CN3)C4=CC=CC=C4)=O)C2=O)(SCC1C[N+]=5C=CC(CCS(=O)(=O)O)=CC5)[H]
Synonyms:
  • 1-[(6R,7R)-2-Carboxy-7-[(R)-2-(5-carboxy-4-imidazolylcarboxamido)-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylmethyl]pyridino-4-ethylsulfonate
  • 2-(1-{[(6R,7R)-2-Carboxy-7-{[(2R)-2-{[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino}-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridinium-4-yl)ethanesulfonate
  • 7-b-[D(-)-a-(4-Carboxyimidazole-5-carboxamido)phenylacetamido]-3-(4-b-sulfoethylpyridinium)methyl-3-cephem-4-carboxylic Acid
  • 84880-03-5
  • Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt
  • Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt
  • Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]-
  • U 63196
  • Cefpimizole
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