CAS 84891-19-0

N(alpha)-fmoc-N(im)-benzyloxymethyl-L-histidine

Description:

N(alpha)-Fmoc-N(im)-benzyloxymethyl-L-histidine is a derivative of the amino acid histidine, characterized by the presence of a fluorenylmethyloxycarbonyl (Fmoc) protecting group at the alpha-amino group and a benzyloxymethyl group at the imidazole side chain. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis, due to its ability to protect functional groups during the coupling process. The Fmoc group is known for its stability under basic conditions and can be removed under mild acidic conditions, allowing for selective deprotection. The benzyloxymethyl group enhances the solubility and stability of the histidine residue, facilitating its incorporation into peptides. The compound exhibits characteristics typical of histidine derivatives, including potential for coordination with metal ions due to the imidazole nitrogen, and it may participate in various biochemical interactions. Its unique structure makes it valuable in the development of peptide-based therapeutics and research applications in biochemistry and molecular biology.

Formula: C₂₉H₂₇N₃O₅

Synonyms:

• na-fmoc-P-benzyloxymethyl-L-histidine
• Fmoc-His(Bom)-OH
• Fmoc-His(3-Bom)-Oh
• Fmoc-His(3-Bom)-OH≥ 99% (HPLC)
• Fmoc-L-His(p-Bom)-OH
• N-ALPHA-FMOC-N(IM)-BENZYLOXYMETHYL-L-HISTIDINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-PI-BENZYLOXYMETHYL-L-HISTIDINE
• N-Fmoc-N'-benzyloxymethyl-L-histidine
• FMOC-N-P-BENZYLOXYMETHYL-L-HISTIDINE
• FMOC-HISTIDINE(3-BOM)-OH
• L-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[(phenylmethoxy)methyl]-
• FMOC-HIS(PI-BOM)-OH
• nα-fmoc-π-bom-l-histidine
• (2S)-3-{1-[(benzyloxy)methyl]-1H-imidazol-5-yl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
• (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[3-(phenylmethoxymethyl)imidazol-4-yl]propanoic acid
• (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-((benzyloxy)methyl)-1H-imidazol-5-yl)propanoic acid
• FMOC-HIS(3-BOM)-OH USP/EP/BP
• FMOC-HIS(P-BOM)-OH
• (9H-Fluoren-9-yl)MethOxy]Carbonyl His(Bom)-OH
• N-Fluorenylmethoxycarbonyl-N'-benzyloxymethyl-L-histidine

Fmoc-His(3-Bom)-OH

CAS: 84891-19-0

Fmoc-His(Bom)-OH can be coupled with minimal concomitant racemization, though Bom resists the standard cleavage conditions of Fmoc-SPPS.

Formula: C₂₉H₂₇N₃O₅

Purity: 99.8%

Color and Shape: White Powder

Molecular weight: 497.55

Ref: 01-4027660

Fmoc-His(Bom)-OH

CAS: 84891-19-0

Formula: C₂₉H₂₇N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 497.5418

Ref: IN-DA003QNE

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-((benzyloxy)methyl)-1H-imidazol-5-yl)propanoic acid

CAS: 84891-19-0

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-((benzyloxy)methyl)-1H-imidazol-5-yl)propanoic acid

Purity: 98%

Ref: 54-OR1042200

Fmoc-His(Bom)-OH

CAS: 84891-19-0

Formula: C₂₉H₂₇N₃O₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 497.54

Ref: 7W-GM5227

Fmoc-His(Bom)-OH

CAS: 84891-19-0

Formula: C₂₉H₂₇N₃O₅

Purity: 98%

Molecular weight: 497.551

Ref: 10-F545324