CAS: 849217-64-7 - Foretinib

Formula: C₃₄H₃₄F₂N₄O₆

InChI: InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)

InChI key: InChIKey=CXQHYVUVSFXTMY-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(OCCCN6CCOCC6)C(OC)=CC54)C(F)=C3)CC2

Synonyms:

• 1,1-Cyclopropanedicarboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N′-(4-fluorophenyl)-
• 1-N′-[3-Fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• Exel 2880
• Foretinib
• Gsk 1363089
• Gsk 1363089G
• N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• Xl 880

N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

CAS: 849217-64-7

• Formula: C₃₄H₃₄F₂N₄O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 632.6538

Foretinib

CAS: 849217-64-7

Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 …

• Formula: C₃₄H₃₄F₂N₄O₆
• Purity: 98.07% - 99.7%
• Color and Shape: Solid
• Molecular weight: 632.65

Foretinib

CAS: 849217-64-7

• Formula: C₃₄H₃₄F₂N₄O₆
• Molecular weight: 632.66

Foretinib

CAS: 849217-64-7

• Formula: C₃₄H₃₄F₂N₄O₆
• Molecular weight: 632.65

Foretinib

CAS: 849217-64-7

Inhibits MET, VEGFR2, Ron, AXL, Tie-2, Flt-1, Flt-3 and Flt-4 tyrosine kinases

• Formula: C₃₄H₃₄F₂N₄O₆
• Purity: Min. 95%
• Color and Shape: White To Off-White Solid
• Molecular weight: 632.24464

Foretinib

CAS: 849217-64-7

Applications Foretinib (GSK1363089) is an ATP-competitive inhibitor of hepatocyte growth factor (HGF) and Vascular endothelial …

• Formula: C₃₄H₃₄F₂N₄O₆
• Color and Shape: Neat
• Molecular weight: 632.65