CAS 849217-77-2

Cyclopropanecarboxylic acid,1-[[[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]amino]carbonyl]-

Description:

Cyclopropanecarboxylic acid, 1-[[[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]amino]carbonyl]- is a complex organic compound characterized by its cyclopropane ring structure and a carboxylic acid functional group. The presence of a quinoline moiety, specifically a 6,7-dimethoxy-4-quinolinyl group, suggests potential biological activity, as quinolines are often associated with pharmacological properties. The compound also features an amide linkage due to the carbonyl group attached to the phenyl ring, which can influence its solubility and reactivity. The overall structure indicates that it may exhibit unique chemical properties, such as potential acidity from the carboxylic acid and the ability to participate in hydrogen bonding due to the amide and hydroxyl functionalities. Additionally, the presence of methoxy groups can enhance lipophilicity, potentially affecting its interaction with biological systems. This compound may be of interest in medicinal chemistry and drug development, particularly in the context of targeting specific biological pathways.

Formula: C₂₂H₂₀N₂O₆

Cabozantinib Impurity 8 Sodium Salt

CAS: 849217-77-2

Formula: C₂₂H₁₉N₂O₆·Na

Color and Shape: White To Off-White Solid

Molecular weight: 407.40 22.99

Ref: 4Z-C-284025

Cabozantinib Impurity 8 HCl

CAS: 849217-77-2

Formula: C₂₂H₂₀N₂O₆·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 408.41 36.46

Ref: 4Z-C-284014

Cabozantinib Carboxylic Acid

CAS: 849217-77-2

Formula: C₂₂H₂₀N₂O₆

Molecular weight: 408.41

Ref: ST-EA-CP-C46004

Cabozantinib Des-O-fluoroaniline

Controlled Product

CAS: 849217-77-2

Applications Cabozantinib Des-O-fluoroaniline is a degradation product of Cabozantinib(C051500). Cabozantinib is a small molecule C-Met modulator. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.
References Camp, R., et al.: Cancer, 86, 2259 (1999), Morello, S., et al.: J. Cell Physiol., 189, 285 (2001), Zhang, Y., et al.: Oncogene, 21, 217 (2002), Wells, S., et al.: J. Clin. Oncol., 28, 767 (2010); Wu, C., et al.: J. Pharm. Biomed. Anal., 98, 356 (2014)

Formula: C₂₂H₂₀N₂O₆

Color and Shape: Neat

Molecular weight: 408.4

Ref: TR-C051610

1-[4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylcarbamoyl]-cyclopropanecarboxylic acid

CAS: 849217-77-2

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Formula: C₂₂H₂₀N₂O₆

Purity: Min. 95%

Molecular weight: 408.4 g/mol

Ref: 3D-ZIB21777