CAS 84946-20-3

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole

Description:

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with a chloro group and a 4-fluorobenzyl moiety. This compound typically exhibits properties associated with heterocyclic compounds, such as moderate solubility in organic solvents and potential reactivity due to the presence of halogen substituents. The chloro group can influence the compound's electronic properties and reactivity, while the fluorobenzyl group may enhance lipophilicity and biological activity. As a benzimidazole derivative, it may exhibit pharmacological properties, making it of interest in medicinal chemistry. The compound's molecular weight, melting point, and specific reactivity would depend on its precise structural configuration and the presence of functional groups. Safety data sheets and handling guidelines should be consulted for information on toxicity and safe handling practices, as halogenated compounds can pose environmental and health risks. Overall, 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole represents a class of compounds with potential applications in pharmaceuticals and agrochemicals.

Formula: C₁₄H₁₀ClFN₂

InChI: InChI=1/C14H10ClFN2/c15-14-17-12-3-1-2-4-13(12)18(14)9-10-5-7-11(16)8-6-10/h1-8H,9H2

InChI key: InChIKey=PGXALMVNIRPELS-UHFFFAOYSA-N

SMILES: C(N1C=2C(N=C1Cl)=CC=CC2)C3=CC=C(F)C=C3

Synonyms:

• 1-(4'-Fluorobenzyl)-2-Chlorobenzimidazole
• 1-(4-Fluorobenzyl)-2-Chloro-Benzimidazole
• 1-(4-Fluorophenylmethyl)-2-Chlorobenzimidazole
• 1H-Benzimidazole, 2-chloro-1-[(4-fluorophenyl)methyl]-
• 2-Chloro-1-(4-Fluorobenzyl)-1H-Benzimidazole
• 2-Chloro-1-[(4-Fluorophenyl)Methyl]-1H-Benzimidazole
• 2-Chloro-1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole
• 2-Chloro-1-[(4-fluorophenyl)methyl]benzimidazole
• 3-(4'-Fluorobenzy)-2-Chlorobenzimidazole
• N-Methyl-N-(-Chloroethyl) Aniline
• 2-Chloro-1-(4-fluorobenzyl)benzimidazole
• 1-(4-Flourobenzyl)-2-chlorobenzimidazole
• 1-(4-Fluorobenzyl)-2-chlorobenzimidazole, 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole
• 1-(4-fluorobenzyl)-2-chloro-1H-benzo[d]imidazole
• 1-(4-fluorobenzyl)-2-chlorobenzimidazole (intermediate of mizolastine)
• 1-(4-FLUOROBENZYL)-2-CHLOROBENZIMIDAZOL&
• 2-Chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole(CFMB)
• 1-(4-Fluorobenzyl)-2-Chloro-Be

2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole

CAS: 84946-20-3

Formula: C₁₄H₁₀ClFN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 260.6940

Ref: IN-DA003GU6

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole

CAS: 84946-20-3

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole

Purity: 97%

Molecular weight: 260.69g/mol

Ref: 54-PC5243

2-Chloro-1-(4-fluorobenzyl)benzimidazole

CAS: 84946-20-3

2-Chloro-1-(4-fluorobenzyl)benzimidazole

Purity: ≥98%

Molecular weight: 260.69g/mol

Ref: 54-BUP13676

2-Chloro-1-(4-fluorobenzyl)benzimidazole

CAS: 84946-20-3

2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).

Formula: C₁₄H₁₀ClFN₂

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 260.69

Ref: TM-T7478

2-Chloro-1-(4-fluorobenzyl)benzimidazole

Controlled Product

CAS: 84946-20-3

Applications A novel aldose reductase (ALR2) inhibitor. It is used for preparation of disubstituted benzimidazole derivative as anti-allergic agent (Mizolastine).
References Masson, E., et al.: Drugs, 39, 190 ( 1990), Lindstad, R., et al.: Eur. J. Biochem., 221, 847 (1994), Chien, D., et al.: J. Pharm. Sci., 86, 1180 (1997), Harrison, D., et al.: Biochemistry, 36, 16134 (1997), Da Settimo, F., et al.: J. Med. Chem., 44, 316 (2001),

Formula: C₁₄H₁₀ClFN₂

Color and Shape: Neat

Molecular weight: 260.69

Ref: TR-C366290

2-Chloro-1-(4-fluoro-benzyl)-1H-benzoimidazole

CAS: 84946-20-3

Formula: C₁₄H₁₀ClFN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 260.7

Ref: 10-F091066