CAS 849550-67-0

Cevipabulin fumarate

CAS: 849550-67-0

Cevipabulin fumarate is a synthetic chemical compound, which is a small molecule derived from chemical synthesis with potent antineoplastic properties. It functions as a microtubule stabilizer, binding to the colchicine binding site on beta-tubulin, thereby disrupting the dynamic instability of microtubules. This disruption inhibits the polymerization and depolymerization of tubulin dimers, ultimately arresting the cell cycle and inducing apoptosis in cancer cells.

Formula: C₂₂H₂₂ClF₅N₆O₅

Purity: Min. 95%

Molecular weight: 580.9 g/mol

Ref: 3D-ZIB55067

Cevipabulin fumarate

CAS: 849550-67-0

Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).

Formula: C₂₂H₂₂ClF₅N₆O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 580.89

Ref: TM-T10772L