CAS 849811-78-5

Pitavastatin Methyl Ester

Description:

Pitavastatin Methyl Ester is a synthetic compound belonging to the class of statins, which are primarily used to lower cholesterol levels in the blood. It is an ester derivative of pitavastatin, a potent HMG-CoA reductase inhibitor. The chemical structure of Pitavastatin Methyl Ester includes a methyl ester functional group, which influences its solubility and bioavailability. This compound exhibits lipid-lowering properties by inhibiting the enzyme responsible for cholesterol synthesis in the liver, thereby reducing low-density lipoprotein (LDL) cholesterol and triglycerides while potentially increasing high-density lipoprotein (HDL) cholesterol. In addition to its cholesterol-lowering effects, pitavastatin has been studied for its potential anti-inflammatory and antioxidant properties. The pharmacokinetics of this compound suggest that it has a favorable absorption profile, with metabolism primarily occurring in the liver. As with other statins, it may have side effects, including muscle pain and liver enzyme alterations, necessitating monitoring during therapy. Overall, Pitavastatin Methyl Ester represents a significant advancement in the management of dyslipidemia.

(3R,5S,E)-Methyl 7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate

CAS: 849811-78-5

Formula: C₂₆H₂₆FNO₄

Purity: %

Molecular weight: 435.4873

Ref: IN-DA008HDU

Pitavastatin Impurity 27

CAS: 849811-78-5

Formula: C₂₆H₂₆FNO₄

Color and Shape: White To Off-White Solid

Molecular weight: 435.50

Ref: 4Z-P-6426

Pitavastatin Methyl Ester

CAS: 849811-78-5

Formula: C₂₆H₂₆FNO₄

Molecular weight: 435.50

Ref: ST-EA-CP-P23003

Pitavastatin Methyl Ester

Controlled Product

CAS: 849811-78-5

Formula: C₂₆H₂₆FNO₄

Color and Shape: Neat

Molecular weight: 435.487

Ref: TR-P531015

((3R,5S,6E)-Methyl-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin -3-yl)-3,5-dihydroxyhept-6-enoate

CAS: 849811-78-5

((3R,5S,6E)-Methyl-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin -3-yl)-3,5-dihydroxyhept-6-enoate is a metabolite of the drug product. It is a white to off-white crystalline powder that is soluble in methanol and insoluble in water. This compound has been shown to be an impurity standard for HPLC analysis of the drug product. ((3R,5S,6E)-Methyl-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin -3-yl)-3,5-dihydroxyhept-6-enoate has been used in metabolism studies and pharmacopoeia as a reference substance for the analytical testing of drugs. It can also be synthesized for research purposes.

Purity: Min. 95%

Ref: 3D-IM145424

Pitavastatin methyl ester

CAS: 849811-78-5

Pitavastatin methyl ester is the methyl ester derivative of Pitavastatin -- a competitive inhibitor of HMG-CoA reductase and an anti-lipemic agent.

Formula: C₂₆H₂₆FNO₄

Color and Shape: Solid

Molecular weight: 435.49

Ref: TM-T68566