CAS 849832-73-1

2,2,2-Trifluoroacetic acid (2Z)-2-(2-piperazinylidene)hydrazide

Description:

2,2,2-Trifluoroacetic acid (2Z)-2-(2-piperazinylidene)hydrazide is a chemical compound characterized by its unique structural features and functional groups. The presence of trifluoroacetic acid contributes to its strong acidity and potential reactivity, particularly in forming stable complexes with various nucleophiles. The hydrazide functional group indicates that it can participate in condensation reactions, making it useful in synthetic organic chemistry. The piperazine moiety introduces basicity and potential for forming hydrogen bonds, enhancing its solubility in polar solvents. This compound may exhibit biological activity due to its structural components, which can interact with biological targets. Additionally, the trifluoromethyl groups can influence the lipophilicity and metabolic stability of the compound. Overall, 2,2,2-Trifluoroacetic acid (2Z)-2-(2-piperazinylidene)hydrazide is a versatile molecule with potential applications in pharmaceuticals and materials science, although specific biological or chemical properties would require further investigation through empirical studies.

Formula: C₆H₉F₃N₄O

InChI: InChI=1S/C6H9F3N4O/c7-6(8,9)5(14)13-12-4-3-10-1-2-11-4/h10H,1-3H2,(H,11,12)(H,13,14)

InChI key: InChIKey=RKIDLJBEMIARHI-UHFFFAOYSA-N

SMILES: N(\NC(C(F)(F)F)=O)=C\1/CNCCN1

Synonyms:

• Acetic acid, trifluoro-, (2Z)-2-(2-piperazinylidene)hydrazide
• N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide
• 2,2,2-Trifluoroacetic acid (2Z)-2-(2-piperazinylidene)hydrazide
• N′-[(2Z)-Piperazin-2-ylidene]trifluoroacetohydrazide
• Acetic acid, 2,2,2-trifluoro-, (2Z)-2-(2-piperazinylidene)hydrazide

Acetic acid, 2,​2,​2-​trifluoro-​, (2Z)​-​2-​(2-​piperazinylidene)​hydrazide

CAS: 849832-73-1

Formula: C₆H₉F₃N₄O

Purity: 97%

Color and Shape: Solid

Molecular weight: 210.1571

Ref: IN-DA00G3RV

(2Z)-2-(2-Piperazinylidene)hydrazide trifluoroacetate

CAS: 849832-73-1

(2Z)-2-(2-Piperazinylidene)hydrazide trifluoroacetate

Molecular weight: 210.15707g/mol

Ref: 54-PC106134

Sitagliptin Impurity 94

CAS: 849832-73-1

Formula: C₆H₉F₃N₄O

Molecular weight: 210.16

Ref: 4Z-S-20123

N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide

CAS: 849832-73-1

N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide (NPI) is a hydrazine derivative with cyclization and chlorination. It is an oxychloride of N-(2-chloroethyl)hydrazinecarbothioamide. Hydrazine derivatives are mainly used as synthetic intermediates for the production of pharmaceuticals and agrochemicals. Trifluoroacetate is a chemical compound that has been shown to be active against the growth of Mycobacterium tuberculosis and Mycobacterium avium complex. Trifluoroacetate inhibits the biosynthesis of mycolic acids, which are essential components of the cell wall in these bacteria. The mechanism of action of trifluoroacetate involves inhibition of the enzyme mycolic acid synthase through covalent modification by forming an adduct with its active site cysteine residue.

Formula: C₆H₉F₃N₄O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 210.16 g/mol

Ref: 3D-FP95705

N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide

Controlled Product

CAS: 849832-73-1

Applications Sitagliptin intermediate.
References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),

Formula: C₆H₉F₃N₄O

Color and Shape: Neat

Molecular weight: 210.16

Ref: TR-P481000

Sitagliptin Impurity 49

CAS: 849832-73-1

Formula: C₆H₉F₃N₄O

Molecular weight: 210.16

Ref: ST-EA-CP-S3024