CAS 85-56-3

2-(4-Chlorobenzoyl)benzoic acid

Description:

2-(4-Chlorobenzoyl)benzoic acid, also known as benzoyl-4-chlorobenzoic acid, is an aromatic carboxylic acid characterized by its structure, which features a benzoic acid moiety substituted with a 4-chlorobenzoyl group. This compound typically appears as a white to off-white crystalline solid. It is sparingly soluble in water but more soluble in organic solvents such as ethanol and acetone. The presence of the chlorobenzoyl group enhances its reactivity, making it useful in various chemical syntheses and applications, including pharmaceuticals and agrochemicals. The compound exhibits typical acid properties, including the ability to donate protons in solution, and may participate in various chemical reactions such as esterification and acylation. Additionally, it may have specific biological activities, which can be of interest in medicinal chemistry. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₁₄H₉ClO₃

InChI: InChI=1S/C14H9ClO3/c15-10-7-5-9(6-8-10)13(16)11-3-1-2-4-12(11)14(17)18/h1-8H,(H,17,18)

InChI key: InChIKey=YWECCEXWKFHHQJ-UHFFFAOYSA-N

SMILES: C(=O)(C1=C(C(O)=O)C=CC=C1)C2=CC=C(Cl)C=C2

Synonyms:

• 2-(p-Chlorobenzoyl)benzoic acid
• 2-Carboxy-4-chlorobenzophenone
• 4'-Chlorobenzophenone-2-carboxylic acid
• Benzoic acid, 2-(4-chlorobenzoyl)-
• Benzoic acid, o-(p-chlorobenzoyl)-
• CBB
• NSC 7825
• o-(4-Chlorobenzoyl)benzoic acid
• o-(p-Chlorobenzoyl)benzoic acid
• 2-(4-chlorobenzoyl)-benzoic acid
• 2-(4-Chlorobenzoyl)benzoic acid

4'-Chlorobenzophenone-2-carboxylic Acid

CAS: 85-56-3

Formula: C₁₄H₉ClO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 260.67

Ref: 3B-C1074

2-(4-Chlorobenzoyl)benzoic acid

CAS: 85-56-3

Formula: C₁₄H₉ClO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 260.6725

Ref: IN-DA003L6Q

2-(4-Chlorobenzoyl)benzoic acid

CAS: 85-56-3

2-(4-Chlorobenzoyl)benzoic acid

Purity: 98%

Molecular weight: 260.67g/mol

Ref: 54-OR5178

2-(4’-Chlorobenzoyl)benzoic Acid

Controlled Product

CAS: 85-56-3

Applications 2-(4’-Chlorobenzoyl)benzoic Acid (cas# 85-56-3) is a compound useful in organic synthesis.

Formula: C₁₄H₉ClO₃

Color and Shape: Neat

Molecular weight: 260.672

Ref: TR-C364555

2-(4'-Chlorobenzoyl)benzoic acid

CAS: 85-56-3

2-(4'-Chlorobenzoyl)benzoic acid (2-CBA) is a sulfa drug that inhibits bacterial growth by blocking the synthesis of folic acid. It is also known to be luminescent and can be used in techniques such as luminescent probes. 2-CBA has antibacterial activity and can inhibit bacterial growth in a chromatographic method. 2-CBA is chemically stable and has been shown to have antibacterial properties against gram-positive bacteria, including Bacillus subtilis and Staphylococcus aureus. 2-CBA also has the ability to react with phthalazinone, an inhibitor of glutamine synthetase, which is involved in the production of ATP from ADP. This reaction results in the formation of an unstable intermediate which decomposes into CO2 and benzoic acid.

Formula: C₁₄H₉ClO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 260.67 g/mol

Ref: 3D-FC20197

2-(4-Chlorobenzoyl)benzoic acid

CAS: 85-56-3

Formula: C₁₄H₉ClO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 260.67

Ref: 10-F215727

2-(4’-Chlorobenzoyl)benzoic Acid-d4

Controlled Product

CAS: 85-56-3

Applications 2-(4’-Chlorobenzoyl)benzoic Acid-d4 is an intermediate in the synthesis of labelled Chlorthalidone. Chlorthalidone is used as a diuretic; antihypertensive.
References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966); Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972); Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985);

Formula: C₁₄D₄H₅ClO₃

Color and Shape: Neat

Molecular weight: 264.697

Ref: TR-C364557

2-(4\'-Chlorobenzoyl)benzoic Acid

CAS: 85-56-3

Formula: C₁₄H₉ClO₃

Molecular weight: 260.67

Ref: ST-EA-CP-F116025