CAS 85-61-0: Coenzyme A
Description:Coenzyme A (CoA) is a vital cofactor in various biochemical reactions, primarily involved in the metabolism of fatty acids and carbohydrates. It is a complex molecule composed of adenosine, pantothenic acid (vitamin B5), and a mercaptoethylamine group. CoA plays a crucial role in the formation of acetyl-CoA, which is a key substrate for the citric acid cycle, facilitating energy production in cells. The substance is characterized by its ability to form thioester bonds, which are essential for the activation of acyl groups in metabolic pathways. Coenzyme A is soluble in water and exhibits a high degree of reactivity due to the presence of its thiol group, allowing it to participate in various enzymatic reactions. Its structure enables it to act as a carrier for acyl groups, making it indispensable in the synthesis and degradation of fatty acids and the metabolism of amino acids. Overall, Coenzyme A is integral to cellular energy metabolism and the synthesis of important biomolecules.
Formula:C21H36N7O16P3S
InChI:InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1
InChI key:InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-N
SMILES:O=C(NCCS)CCNC(=O)C(O)C(C)(C)COP(=O)(O)OP(=O)(O)OCC1OC(N2C=NC=3C(=NC=NC32)N)C(O)C1OP(=O)(O)O
- Synonyms:
- <span class="text-smallcaps">D</span>-Coenzyme A
- Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R)-3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester
- Adenosine 5'-(trihydrogen diphosphate), 3'-(dihydrogen phosphate), P'-[3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, (R)-
- Aluzime
- COA
- CoASH
- Coa-Sh
- Coalip
- Coenzym A
- Coenzyme A Free Acid From Yeast
- See more synonyms
- Coenzyme A Hydrate
- Coenzyme A, free acid, lyophilized, 75%
- Coenzyme A, free acid, lyophilized, min. 75% (enzym.)
- Coenzyme ASH
- Coenzyme a, free acid
- D-Coenzyme A
- Lucina
- Reduced CoA
- Thiol-CoA
- [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
- [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3S)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
- [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl 3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
- coenzima A
- Coenzyme A
