CAS 85-63-2

(-)-laudanosine

Description:

(-)-Laudanosine is an alkaloid derived from the opium poppy, specifically known for its presence in various plant species. It is characterized by its chemical structure, which includes a phenolic group and a methoxy group, contributing to its biological activity. The compound is a chiral molecule, with the (-) designation indicating its specific stereochemistry. (-)-Laudanosine has been studied for its potential effects on the central nervous system, including its role as a neuromodulator and its interactions with various neurotransmitter systems. It exhibits a range of pharmacological properties, including muscle relaxant and analgesic effects, although its clinical applications are limited. The substance is also notable for its low toxicity compared to other opiate derivatives. In laboratory settings, (-)-laudanosine can be synthesized or extracted for research purposes, and its behavior in biological systems continues to be a subject of investigation, particularly in the context of pain management and anesthetic applications.

Formula: C₂₁H₂₇NO₄

Synonyms:

• (R)-Laudanosine
• N-methyl-1,2-dihydropapaverine
• (-)-(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
• (R)-1-(3',4'-dimethoxybenzyl)-2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
• Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R)-
• (R)-1-(3,4-dimethoxybenzyl)-
• (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
• cis-Atracurium EP Impurity C
• (-)-laudanosine
• Cisatracurium Besilate Impurity 3
• Impurities of atracurium391
• (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium
• AtracuriuM Besylate iMpurity C
• Cisatracurium Besilate EP Impurity C (R-Laudanosine)

(R)-Laudanosine ((R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline)

CAS: 85-63-2

Compounds containing a quinoline or isoquinoline ring-system, whether or not hydrogenated, not further fused, excluding drugs and pesticides

Formula: C₂₁H₂₇NO₄

Color and Shape: White Off-White Solid

Molecular weight: 357.19401

Ref: 45-1A02700

Cisatracurium Besilate EP Impurity C ((R)-Laudanosine)

CAS: 85-63-2

Formula: C₂₁H₂₇NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 357.45

Ref: 4Z-A-755

R-Laudanosine

CAS: 85-63-2

Formula: C₂₁H₂₇NO₄

Molecular weight: 357.45

Ref: ST-EA-CP-A131068

(R)-Laudanosine

CAS: 85-63-2

Applications (R)-Laudanosine is an isomer of (S)-Laudanosine (L178525), a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986); Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992); Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993)

Formula: C₂₁H₂₇NO₄

Color and Shape: Neat

Molecular weight: 357.44

Ref: TR-L178520

(R)-Laudanosine

CAS: 85-63-2

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Formula: C₂₁H₂₇NO₄

Purity: Min. 95%

Molecular weight: 357.4 g/mol

Ref: 3D-AAA08563