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CAS 850568-73-9

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(3-chloro-4-fluoro-5-nitro-phenyl)boronic acid

Description:
(3-Chloro-4-fluoro-5-nitro-phenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that is substituted with chlorine, fluorine, and nitro groups. This compound typically exhibits a white to off-white solid appearance and is soluble in polar solvents such as water and alcohols, owing to the boronic acid moiety. The presence of the electron-withdrawing nitro group and halogen substituents can influence its reactivity and stability, making it useful in various chemical reactions, particularly in Suzuki coupling reactions for the synthesis of biaryl compounds. Additionally, boronic acids are known for their ability to form reversible complexes with diols, which can be exploited in sensor applications and drug design. The compound's unique combination of functional groups may also impart specific biological activities, making it of interest in medicinal chemistry. Proper handling and storage are essential due to potential reactivity and toxicity associated with some of its components.
Formula:C6H4BClFNO4
InChI:InChI=1/C6H4BClFNO4/c8-4-1-3(7(11)12)2-5(6(4)9)10(13)14/h1-2,11-12H
SMILES:c1c(cc(c(c1Cl)F)N(=O)=O)B(O)O
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