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CAS 85079-48-7

:

PbTx 3

Description:
PbTx 3, also known as a potent neurotoxin, is a compound derived from marine organisms, specifically certain species of dinoflagellates. It is classified as a member of the brevetoxin family, which are known for their ability to bind to voltage-gated sodium channels in nerve cells, leading to increased neuronal excitability. This characteristic makes PbTx 3 particularly relevant in studies of neurobiology and toxicology. The compound is often associated with harmful algal blooms, which can have significant ecological and health impacts. PbTx 3 is lipophilic, allowing it to accumulate in marine food webs, posing risks to marine life and humans who consume contaminated seafood. Its structure features a complex polyether backbone, contributing to its biological activity and toxicity. Research on PbTx 3 continues to explore its mechanisms of action, potential therapeutic applications, and environmental implications, particularly in relation to marine ecosystems and public health.
Formula:C50H72O14
InChI:InChI=1/C49H72O14/c1-24(23-50)13-27-16-38(51)49(7)42(53-27)18-33-34(61-49)17-32-28(54-33)9-8-10-29-36(56-32)22-48(6)41(57-29)20-40-46(4,63-48)12-11-30-44(60-40)25(2)14-31-37(55-30)21-47(5)39(58-31)19-35-45(62-47)26(3)15-43(52)59-35/h15,25,27-42,44-45,50-51H,1,8-14,16-23H2,2-7H3/t25-,27-,28-,29+,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,40+,41-,42-,44-,45-,46-,47+,48+,49+/m1/s1
InChI key:InChIKey=BKMHDYJRAAJTAD-RXUQWMQDSA-N
SMILES:C[C@@]12[C@](O[C@]3(C)[C@@](C1)(O[C@@]4([C@@](C=CC3)(O[C@@]5([C@@](C4)(O[C@]6(C)[C@@](C5)(O[C@H](CC(CO)=C)C[C@@H]6O)[H])[H])[H])[H])[H])[H])(C[C@]7([C@](C)(O2)CC[C@]8([C@](O7)([C@H](C)C[C@]9([C@](O8)(C[C@@]%10(C)[C@](O9)(C[C@]%11([C@](O%10)(C(C)=CC(=O)O%11)[H])[H])[H])[H])[H])[H])[H])[H])[H]
Synonyms:
  • 1H-Pyrano[2′′,3′′:5′,6′]pyrano[2′,3′:5,6]pyrano[3,2-b]pyrano[2′′′′′′,3′′′′′′:5′′′′′,6′′′′′]pyrano[2′′′′′,3′′′′′:5′′′′,6′′′′]pyrano[2′′′′,3′′′′:6′′′,7′′′]oxepino[2′′′,3′′′:6′′,7′′]oxepino[2′′,3′′:5′,6′]pyrano[2′,3′:5,6]pyrano[2,3-g]oxocin, brevetoxin B deriv.
  • 42-Deoxo-42-hydroxybrevetoxin B
  • 85079-48-7
  • Brevetoxin 3
  • Brevetoxin B, 42-deoxo-42-hydroxy-
  • Brevetoxin PbTx 3
  • Brevetoxin T 17
  • Dihydrobrevetoxin B
  • GB 3 toxin
  • PbTx 3
  • See more synonyms
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Found 2 products.
  • Brevetoxin-3
    Targetmol
    + Info

    Brevetoxin-3

    CAS:
    <p>Brevetoxin-3 activates Na+ channels, binding strongly to site 5, preventing their inactivation.</p>
    Formula:C50H72O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:897.112

    Ref: TM-T10609

  • Brevetoxin-3
    Biosynth
    + Info

    Brevetoxin-3

    CAS:
    <p>Brevetoxin-3 is a potent neurotoxin, which is produced by marine dinoflagellates, specifically from the genus Karenia. It acts by binding to voltage-gated sodium channels on neuronal cells, disrupting normal cellular function by keeping these channels open. This leads to continuous sodium influx, resulting in prolonged depolarization of nerve cells. The modulation of sodium channel activity by brevetoxin-3 is a key factor in the manifestation of neurotoxic effects.</p>
    Formula:C50H72O14
    Purity:Min. 95%
    Molecular weight:897.1 g/mol

    Ref: 3D-KDA07948

    1mg
    7,424.00€