CAS 85081-18-1

[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol

Description:

The chemical substance with the name "[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol" and CAS number "85081-18-1" is a complex organic compound characterized by its unique structural features, including a hexahydroquinolizine framework and multiple methoxy groups. This compound exhibits chirality due to the presence of stereocenters, which can influence its biological activity and interactions. The methoxy groups contribute to its solubility and reactivity, while the branched alkyl substituent (2-methylpropyl) may enhance its lipophilicity. Such compounds are often studied for their potential pharmacological properties, including effects on the central nervous system or other biological pathways. The specific stereochemistry and functional groups present in this molecule can lead to diverse chemical behaviors, making it a subject of interest in medicinal chemistry and drug development. However, detailed studies on its biological activity, toxicity, and therapeutic potential would be necessary to fully understand its implications in various applications.

Formula: C₁₉H₂₉NO₃

2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2R,3R,11bR)-

CAS: 85081-18-1

Formula: C₁₉H₂₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 319.4385

Ref: IN-DA004RQH

NBI-98782

CAS: 85081-18-1

NBI-98782

Purity: ≥98%

Molecular weight: 319.44g/mol

Ref: 54-BUP07119

Tetrabenazine Impurity 60 (2R,3R,11bR)

CAS: 85081-18-1

Formula: C₁₉H₂₉NO₃

Color and Shape: Off-White Solid

Molecular weight: 319.45

Ref: 4Z-T-7837

NBI-98782

CAS: 85081-18-1

NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)

Formula: C₁₉H₂₉NO₃

Purity: 99.29%

Color and Shape: Solid

Molecular weight: 319.44

Ref: TM-T7563

(+)-α-Dihydrotetrabenazine

Controlled Product

CAS: 85081-18-1

Applications (+)-α-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.
References Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)

Formula: C₁₉H₂₉NO₃

Color and Shape: Neat

Molecular weight: 319.44

Ref: TR-D453615

α-Dihydrotetrabenazine-D7

Controlled Product

CAS: 85081-18-1

Formula: C₁₉D₇H₂₂NO₃

Color and Shape: Neat

Molecular weight: 326.482

Ref: TR-D453619

(+)-α-Dihydrotetrabenazine-13C2D6

Controlled Product

CAS: 85081-18-1

Applications (+)-α-Dihydrotetrabenazine-13C2D6 is the isotope labelled analog of (+)-α-Dihydrotetrabenazine (D453615); a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.
References Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)

Formula: C₂C₁₇D₆H₂₃NO₃

Color and Shape: Neat

Molecular weight: 327.461

Ref: TR-D453617

Tetrabenazine Related Impurity 27 (2R,3R,11bR)

CAS: 85081-18-1

Formula: C₁₉H₂₉NO₃

Molecular weight: 319.45

Ref: ST-EA-CP-T104028