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CAS 851392-68-2

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Fmoc-Dab(Mtt)-OH

Description:
Fmoc-Dab(Mtt)-OH, with the CAS number 851392-68-2, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of 2,4-diaminobutyric acid (Dab) and features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized for the protection of amino groups during peptide synthesis. The Mtt (4-methyltrityl) group serves as an additional protective moiety for the side chain amine, enhancing the compound's stability and facilitating selective deprotection. This compound is typically characterized by its solid state at room temperature, and it is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Fmoc-Dab(Mtt)-OH is particularly valuable in the synthesis of peptides that require specific modifications or functionalities, allowing for the incorporation of unique amino acid sequences. Its use in solid-phase peptide synthesis (SPPS) enables the efficient assembly of complex peptides, making it a crucial reagent in the fields of biochemistry and medicinal chemistry.
Formula:C39H36N2O4
InChI:1S/C39H36N2O4/c1-27-20-22-30(23-21-27)39(28-12-4-2-5-13-28,29-14-6-3-7-15-29)40-25-24-36(37(42)43)41-38(44)45-26-35-33-18-10-8-16-31(33)32-17-9-11-19-34(32)35/h2-23,35-36,40H,24-26H2,1H3,(H,41,44)(H,42,43)/t36-/m0/s1
Synonyms:
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(diphenyl(p-tolyl)methylamino)butanoic acid
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