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CAS 851536-75-9

:

Biolimus A9

Description:
Biolimus A9 is a synthetic derivative of rapamycin, a macrolide compound known for its immunosuppressive and antiproliferative properties. It is primarily utilized in the medical field, particularly in drug-eluting stents, to prevent restenosis by inhibiting smooth muscle cell proliferation and promoting vascular healing. Biolimus A9 exhibits a high affinity for the mTOR (mammalian target of rapamycin) pathway, which plays a crucial role in cell growth and metabolism. The compound is characterized by its lipophilicity, which enhances its ability to penetrate cell membranes and exert its pharmacological effects. Additionally, Biolimus A9 has a favorable safety profile, making it a viable option for long-term applications in cardiovascular interventions. Its efficacy and safety have been evaluated in various clinical studies, demonstrating its potential to improve patient outcomes in the context of coronary artery disease. Overall, Biolimus A9 represents a significant advancement in the development of targeted therapies for vascular diseases.
Formula:C55H87NO14
InChI:InChI=1S/C55H87NO14/c1-12-67-26-27-68-45-24-22-41(31-48(45)65-10)30-37(5)47-33-44(57)36(4)29-39(7)50(59)51(66-11)49(58)38(6)28-34(2)18-14-13-15-19-35(3)46(64-9)32-42-23-21-40(8)55(63,70-42)52(60)53(61)56-25-17-16-20-43(56)54(62)69-47/h13-15,18-19,29,34,36-38,40-43,45-48,50-51,59,63H,12,16-17,20-28,30-33H2,1-11H3/b15-13+,18-14+,35-19+,39-29+/t34-,36-,37-,38-,40-,41+,42+,43+,45-,46+,47+,48-,50-,51+,55-/m1/s1
InChI key:InChIKey=YYSFXUWWPNHNAZ-PKJQJFMNSA-N
SMILES:O=C1N2[C@](C(=O)O[C@]([C@@H](C[C@H]3C[C@@H](OC)[C@H](OCCOCC)CC3)C)(CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(/C)\[C@@H](OC)C[C@]4(O[C@@](O)(C1=O)[C@H](C)CC4)[H])[H])(CCCC2)[H]
Synonyms:
  • 42-O-(2-Ethoxyethyl)rapamycin
  • 40-O-(2-Ethoxyethyl)rapamycin
  • Rapamycin, 42-O-(2-ethoxyethyl)-
  • Ba 9
  • Biolimus A9
  • UMiroliMus
  • BioliMus A9 UMiroliMus
  • BioliMus, BioliMus A9, TRM 986
  • BioliMus
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Found 3 products.
  • Umirolimus
    Indagoo
    + Info

    Umirolimus

    CAS:
    Formula:C55H87NO14
    Purity:95%
    Molecular weight:986.2776

    Ref: IN-DA00G7A3

    1mg
    252.00€
    5mg
    577.00€
    10mg
    To inquire
  • Umirolimus
    Targetmol
    + Info

    Umirolimus

    CAS:
    <p>Umirolimus, a sirolimus derivative, boosts anti-inflammatory/antiproliferative effects &amp; offers better pharmacokinetics.</p>
    Formula:C55H87NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:986.294

    Ref: TM-T26309

  • Umirolimus
    TRC
    + Info

    Umirolimus

    Controlled Product
    CAS:
    Formula:C55H87NO14
    Color and Shape:Neat
    Molecular weight:986.278

    Ref: TR-U710005

    25mg
    1,509.00€