CAS 85175-65-1

3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2h-3-benzazepin-2-one

Description:

3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one is a chemical compound characterized by its complex bicyclic structure, which includes a benzazepine core. This compound features a chloropropyl substituent, contributing to its potential reactivity and biological activity. The presence of methoxy groups at the 7 and 8 positions enhances its lipophilicity, which may influence its pharmacokinetic properties. The tetrahydro configuration indicates that the compound is saturated, which can affect its stability and interaction with biological targets. As a benzazepine derivative, it may exhibit various pharmacological activities, potentially including effects on the central nervous system. The compound's CAS number, 85175-65-1, allows for precise identification in chemical databases and literature. Overall, this substance is of interest in medicinal chemistry, particularly for its potential therapeutic applications, although specific biological activities and mechanisms would require further investigation.

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

CAS: 85175-65-1

Formula: C₁₅H₂₀ClNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 297.7772

Ref: IN-DA00G2BW

Ivabradine Impurity 8

CAS: 85175-65-1

Formula: C₁₅H₂₀ClNO₃

Molecular weight: 297.78

Ref: 4Z-I-3033

3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one

Controlled Product

CAS: 85175-65-1

Formula: C₁₅H₂₀ClNO₃

Color and Shape: Neat

Molecular weight: 297.777

Ref: TR-C375260

3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d6

Controlled Product

CAS: 85175-65-1

Applications 3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one is an impurity in the synthesis of Ivabradine (I940500), a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.
References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),

Formula: C₁₅D₆H₁₄ClNO₃

Color and Shape: Neat

Molecular weight: 303.814

Ref: TR-C375262