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CAS 851881-60-2

:

ADX 47273

Description:
ADX 47273, with the CAS number 851881-60-2, is a chemical compound that has garnered interest in pharmaceutical research, particularly for its potential applications in treating neurological disorders. It is classified as a selective antagonist of the metabotropic glutamate receptor subtype 2 (mGluR2), which plays a crucial role in modulating neurotransmission and synaptic plasticity. The compound is characterized by its ability to influence glutamate signaling pathways, potentially offering therapeutic benefits in conditions such as anxiety, depression, and schizophrenia. ADX 47273 is typically studied in preclinical models to evaluate its efficacy and safety profile. Its chemical structure includes specific functional groups that contribute to its biological activity, although detailed structural information is often proprietary. As with many investigational compounds, ongoing research aims to elucidate its pharmacokinetics, pharmacodynamics, and overall therapeutic potential, making it a subject of interest in the field of neuropharmacology.
Formula:C20H17F2N3O2
InChI:InChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m0/s1
InChI key:InChIKey=VXQCCZHCFBHTTD-HNNXBMFYSA-N
SMILES:C(=O)(N1C[C@@H](C2=NC(=NO2)C3=CC=C(F)C=C3)CCC1)C4=CC=C(F)C=C4
Synonyms:
  • Methanone, (4-fluorophenyl)[(3S)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
  • ADX 47273
  • (4-Fluorophenyl)[(3S)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone
  • (4-Fluorophenyl)-[(3S)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl]methanone
  • Piperidine, 1-(4-fluorobenzoyl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-, (3S)-
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Found 4 products.