CAS 852-19-7

sulfapyrazole

Description:

Sulfapyrazole is a sulfonamide antibiotic that belongs to the class of pyrazole derivatives. It is primarily characterized by its ability to inhibit bacterial growth by interfering with folic acid synthesis, which is essential for bacterial cell metabolism. The compound features a pyrazole ring structure, which contributes to its pharmacological properties. Sulfapyrazole is typically administered in its sodium salt form and is known for its moderate solubility in water. It has been used in the treatment of various infections, particularly those caused by susceptible strains of bacteria. The compound exhibits a range of biological activities, including anti-inflammatory effects, and has been studied for its potential use in various therapeutic applications. However, like other sulfonamides, sulfapyrazole may cause allergic reactions or adverse effects in some individuals. Its use has declined with the advent of newer antibiotics, but it remains a significant compound in the study of antimicrobial agents. Proper handling and dosage are essential to minimize potential side effects and ensure efficacy.

Formula: C₁₆H₁₆N₄O₂S

InChI: InChI=1/C16H16N4O2S/c1-12-11-16(20(18-12)14-5-3-2-4-6-14)19-23(21,22)15-9-7-13(17)8-10-15/h2-11,19H,17H2,1H3

InChI key: InChIKey=MTERSQYMYBGZTP-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=C(N)C=C1)C=2N(N=C(C)C2)C3=CC=CC=C3

Synonyms:

• 1-Phenyl-3-methyl-5-sulfanilamidopyrazole
• 3-(p-Aminobenzosulfoamido)-2-phenyl-5-methylpyrazole
• 3-Methyl-1-phenyl-5-sulfanilamidopyrazole
• 3-Sulfanilamido-5-methyl-2-phenylpyrazole
• 4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
• 5-(p-Aminobenzenesulfonamido)-1-phenyl-3-methylpyrazole
• Benzenesulfonamide, 4-amino-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-
• Ciba 18,605-Ba
• N1-(3-methyl-1-phenylpyrazol-5-yl)sulphanilamide
• N¹-(3-Methyl-1-phenylpyrazol-5-yl)sulfanilamide
• Sulfamethylphenazole
• Sulfanilamide, N¹-(3-methyl-1-phenylpyrazol-5-yl)-
• Sulfazamet
• Vesulong
• N1-(3-Methyl-1-phenylpyrazol-5-yl)sulfanilamide
• Sulfanilamide, N1-(3-methyl-1-phenylpyrazol-5-yl)-
• N'-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)sulfanilamide
• 4-azanyl-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide
• 4-amino-N-(5-methyl-2-phenylpyrazol-3-yl)benzenesulfonamide
• Sulfapyrazole solution,100ppm
• 4-amino-N-(5-methyl-2-phenyl-pyrazol-3-yl)benzenesulfonamide

Sulfamethylphenazole

Controlled Product

CAS: 852-19-7

Formula: C₁₆H₁₆N₄O₂S

Color and Shape: Neat

Molecular weight: 328.39

Ref: 86-MM1108.00

Sulfamethylphenazole

CAS: 852-19-7

Formula: C₁₆H₁₆N₄O₂S

Color and Shape: White Solid

Molecular weight: 328.39

Ref: 04-C16998160

Sulfamethylphenazole

CAS: 852-19-7

Sulfamethylphenazole is a synthetic antibacterial compound, which is derived from sulfonamides. It functions by inhibiting bacterial dihydropteroate synthase, an enzyme crucial for the synthesis of folate in bacteria. This inhibition leads to the depletion of folate coenzymes, which are essential for DNA synthesis and cell replication in bacteria. As a result, Sulfamethylphenazole effectively halts bacterial growth by exploiting the reliance of bacteria on folate synthesis, a pathway absent in human cells, thereby offering selective toxicity.

Formula: C₁₆H₁₆N₄O₂S

Purity: Min. 95%

Molecular weight: 328.4 g/mol

Ref: 3D-AAA85219

Sulfamethylphenazole

CAS: 852-19-7

Formula: C₁₆H₁₆N₄O₂S

Molecular weight: 328.39

Ref: ST-EA-CP-A104002

Sulfamethylphenazole

CAS: 852-19-7

Color and Shape: Neat

Ref: 61-FOR1108.00