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CAS 852062-17-0

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3-Fluoro-5-(trifluoromethyl)-2-pyridinamine

Description:
3-Fluoro-5-(trifluoromethyl)-2-pyridinamine is a chemical compound characterized by its pyridine ring structure, which is a six-membered aromatic ring containing one nitrogen atom. The presence of a fluorine atom at the 3-position and a trifluoromethyl group at the 5-position significantly influences its chemical properties, including its reactivity and polarity. This compound is typically a solid at room temperature and exhibits moderate solubility in polar solvents due to the electronegative fluorine atoms, which can engage in hydrogen bonding and dipole-dipole interactions. The trifluoromethyl group enhances the compound's lipophilicity, making it potentially useful in medicinal chemistry and agrochemical applications. Additionally, the presence of the amino group (-NH2) at the 2-position can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Overall, 3-Fluoro-5-(trifluoromethyl)-2-pyridinamine is of interest for its potential applications in drug development and as a building block in organic synthesis.
Formula:C6H4F4N2O
InChI:InChI=1/C6H4F4N2/c7-4-1-3(6(8,9)10)2-12-5(4)11/h1-2H,(H2,11,12)
InChI key:InChIKey=HAVVQRHBCUBQGG-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1C=C(F)C(N)=NC1
Synonyms:
  • 2-Amino-3-fluoro-5-trifluoromethylpyridine
  • 2-Pyridinamine, 3-fluoro-5-(trifluoromethyl)-
  • 3-Fluoro-5-(trifluoromethyl)-2-pyridinamine
  • 3-Fluoro-5-(trifluoromethyl)pyridin-2-amine
  • 3-Fluoro-5-trifluoromethylpyridin-2-amine
  • 2-Amino-3-fluoro-5-(trifluoromethyl)pyridine 97%
  • 3-Fluoro-5-(trifluoromethyl)pyridin-2-amine, 6-Amino-alpha,alpha,alpha,5-tetrafluoro-3-picoline
  • 2-Amino-3-fluoro-5-(trifluorom
  • 2-Amino-3-fluoro-5-(trifluoromethyl)pyridine,97%
  • 3-Fluoro-5-(trifluoromethyl)pyridine-2-amine
  • See more synonyms
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