CAS 85287-61-2

Cefpimizole sodium

Description:

Cefpimizole sodium is a broad-spectrum cephalosporin antibiotic, primarily used for its antibacterial properties. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The compound is characterized by its beta-lactam structure, which is essential for its mechanism of action, as it inhibits bacterial cell wall synthesis. Cefpimizole sodium is typically administered via injection and is known for its relatively low toxicity profile compared to other antibiotics. It is soluble in water, which facilitates its use in clinical settings. The pharmacokinetics of cefpimizole sodium involve rapid absorption and distribution in the body, with a half-life that allows for effective dosing regimens. As with many antibiotics, the potential for resistance development is a concern, necessitating careful use and adherence to prescribed treatment courses. Overall, cefpimizole sodium represents a valuable option in the arsenal against bacterial infections, particularly in cases where other antibiotics may be ineffective.

Formula: C₂₈H₂₅N₆NaO₁₀S₂

InChI: InChI=1/C28H26N6O10S2.Na/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44;/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44);/q;+1/p-1/t18-,21-,26-;/m1./s1

InChI key: InChIKey=YHZFACAWIXLUTM-MRMAQRIOSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC([C@H](NC(=O)C3=C(C(O)=O)N=CN3)C4=CC=CC=C4)=O)C2=O)(SCC1C[N+]=5C=CC(CCS(=O)(=O)O)=CC5)[H].[Na]

Synonyms:

• Ac 1370
• Ajicef
• Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, monosodium salt
• Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, sodium salt (1:1)
• Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, monosodium salt, [6R-[6α,7β(R*)]]-
• Renilan
• U 63196E
• sodium (6R,7R)-7-{[(2R)-2-{[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino}-2-phenylacetyl]amino}-8-oxo-3-{[4-(2-sulfonatoethyl)pyridinium-1-yl]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium (6R,7R)-7-{[(2S)-2-{[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino}-2-phenylacetyl]amino}-8-oxo-3-{[4-(2-sulfonatoethyl)pyridinium-1-yl]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Cefpimizole sodium

Cefpimizole sodium

CAS: 85287-61-2

Cefpimizole sodium is a Semisynthetic cephalosporin with antibacterial activity.

Formula: C₂₈H₂₅N₆NaO₁₀S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 692.65

Ref: TM-T25223