CAS 85320-68-9

Amosulalol

Description:

Amosulalol is a pharmaceutical compound primarily classified as a beta-blocker, which is used in the management of hypertension and certain cardiac conditions. It exhibits both beta-adrenergic blocking and alpha-adrenergic blocking properties, making it effective in reducing heart rate and lowering blood pressure. The compound is known for its ability to improve blood flow and reduce peripheral resistance, which contributes to its antihypertensive effects. Amosulalol is typically administered orally and is characterized by its moderate lipophilicity, which influences its absorption and distribution in the body. The substance has a relatively short half-life, necessitating multiple doses throughout the day for sustained therapeutic effects. As with many beta-blockers, potential side effects may include fatigue, dizziness, and bradycardia. Its use should be carefully monitored, especially in patients with respiratory conditions or those on other cardiovascular medications. Overall, amosulalol represents a valuable option in the pharmacological management of cardiovascular diseases.

Formula: C₁₈H₂₄N₂O₅S

InChI: InChI=1S/C18H24N2O5S/c1-13-7-8-14(11-18(13)26(19,22)23)15(21)12-20-9-10-25-17-6-4-3-5-16(17)24-2/h3-8,11,15,20-21H,9-10,12H2,1-2H3,(H2,19,22,23)

InChI key: InChIKey=LVEXHFZHOIWIIP-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=CC(C(CNCCOC2=C(OC)C=CC=C2)O)=CC=C1C

Synonyms:

• Benzenesulfonamide, 5-[1-hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methyl-, (±)-
• 5-[1-Hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methylbenzenesulfonamide
• Amosulalol
• Benzenesulfonamide, 5-[1-hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methyl-

Amosulalol

CAS: 85320-68-9

Amosulalol

Purity: ≥98%

Molecular weight: 380.46g/mol

Ref: 54-BUP03972

Amosulalol

CAS: 85320-68-9

Amosulalol is a potent, non-selective antagonist of β-adrenoceptors. It is used for the treatment of hypertension and heart failure. Amosulalol binds to β-adrenoceptors in both the diastolic (relaxing) and systolic (contracting) phases of the cardiac cycle, thereby inhibiting the effects of catecholamines. In addition, it has been shown to inhibit cyclase activity and reduce blood pressure in animal models by reducing the activity of renin. Amosulalol also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Formula: C₁₈H₂₄N₂O₅S

Purity: Min. 95%

Molecular weight: 380.5 g/mol

Ref: 3D-KDA32068

Amosulalol

CAS: 85320-68-9

Amosulalol is a combined alpha and beta adrenoceptor antagonist.

Formula: C₁₈H₂₄N₂O₅S

Purity: 99.5%

Color and Shape: Solid

Molecular weight: 380.46

Ref: TM-T30027