CAS 853299-07-7

Urea,N-[4-[(2-amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-

Description:

The chemical substance known as Urea, N-[4-[(2-amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]- is a complex organic compound characterized by its urea functional group, which is central to its structure. This compound features multiple aromatic rings and substituents, including a pyrimidine moiety and a piperazine group, contributing to its potential biological activity. The presence of trifluoromethyl groups enhances lipophilicity and may influence the compound's pharmacokinetic properties. It is likely to exhibit specific interactions with biological targets, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The compound's molecular structure suggests it may possess properties such as solubility in organic solvents and potential reactivity under certain conditions. Safety and handling precautions should be observed, as with any chemical substance, particularly in laboratory settings. Further studies would be necessary to fully elucidate its properties, including its stability, reactivity, and biological effects.

Formula: C₂₄H₂₆F₃N₇O₂

AUZ 454

CAS: 853299-07-7

Formula: C₂₄H₂₆F₃N₇O₂

Purity: %

Color and Shape: Solid

Molecular weight: 501.5041

Ref: IN-DA00G3SE

AUZ 454

CAS: 853299-07-7

AUZ 454

Purity: ≥95%

Molecular weight: 501.5g/mol

Ref: 54-BUP10463

AUZ 454

CAS: 853299-07-7

AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

Formula: C₂₄H₂₆F₃N₇O₂

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 501.5

Ref: TM-T6866

AUZ 454

CAS: 853299-07-7

AUZ 454 is a small-molecule inhibitor of the protein target Flt3. This drug binds to the active site of Flt3, preventing it from activating downstream signaling pathways. AUZ 454 is an experimental drug that has been shown in preclinical studies to be effective against cancer and a virus strain. The chemical structure of this compound has been determined by titration calorimetry and X-ray crystallography, revealing the binding sites for inhibitors and identifying regions of potential structural changes. The cellular organelles that are affected by AUZ 454 have been identified using sequences from liver cells. This drug is also effective at low doses, which makes it more desirable for use in humans.

Formula: C₂₄H₂₆F₃N₇O₂

Purity: Min. 95%

Molecular weight: 501.5 g/mol

Ref: 3D-DJB29907