CAS 853400-76-7

L-Glutamic acid, glycyl-2-methyl-L-prolyl-

Description:

L-Glutamic acid, glycyl-2-methyl-L-prolyl- is a peptide compound characterized by its structure, which includes the amino acid L-glutamic acid and a glycine residue, along with a 2-methyl-L-proline moiety. This compound is part of a broader class of peptides that play significant roles in biological systems, particularly in protein synthesis and metabolic processes. It exhibits properties typical of amino acids and peptides, such as solubility in water and the ability to form hydrogen bonds, which contribute to its stability and reactivity. The presence of the proline derivative introduces unique conformational characteristics, potentially influencing its biological activity and interactions with other biomolecules. Additionally, this compound may have implications in various fields, including pharmaceuticals and biochemistry, due to its potential roles in neurotransmission and cellular signaling. As with many peptides, its stability and activity can be affected by factors such as pH, temperature, and the presence of other ions or molecules in the environment.

Formula: C₁₃H₂₁N₃O₆

Synonyms:

• Trofinetide(NNZ2566)
• Trofinetide
• TROFINETIDE; NNZ2566 ;NNZ 2566; NNZ-2566
• NNZ-2566
• L-Glutamic acid, glycyl-2-methyl-L-prolyl-
• Trofinetide,NNZ 2566,NNZ2566,Inhibitor,inhibit

Glycyl-2-methyl-L-prolyl-L-glutamic acid

CAS: 853400-76-7

Formula: C₁₃H₂₁N₃O₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 315.3223

Ref: IN-DA008FMG

Trofinetide

CAS: 853400-76-7

Trofinetide

Purity: ≥98%

Molecular weight: 315.32g/mol

Ref: 54-BUP01674

Trofinetide

CAS: 853400-76-7

Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.

Formula: C₁₃H₂₁N₃O₆

Purity: 98.70% - 99.50%

Color and Shape: Solid

Molecular weight: 315.32

Ref: TM-T17171

Trofinetide

CAS: 853400-76-7

Formula: C₁₃H₂₁N₃O₆

Molecular weight: 315.33

Ref: 4Z-T-418001

Trofinetide (>90%)

Controlled Product

CAS: 853400-76-7

Applications Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury.
References Wei, H.H. et al.: J Neuroinflammation. 2009 Aug 5;6:19.

Formula: C₁₃H₂₁N₃O₆

Purity: >90%

Color and Shape: Neat

Molecular weight: 315.32

Ref: TR-T892525

Trofinetide

CAS: 853400-76-7

Trofinetide is a neuroprotective compound that acts as an antioxidant. Trofinetide has been shown to reduce oxidative stress and protect against neuronal death in cells. It also has been shown to improve the clinical response in patients with Alzheimer's disease, and may be used for the treatment of other neurodegenerative disorders such as Parkinson's disease. Trofinetide is orally administered and is metabolized by cytochrome P450 enzymes, which makes it a suitable candidate for specific treatments. The pharmacokinetic properties of trofinetide are not well understood due to its short half-life.

Formula: C₁₃H₂₁N₃O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 315.32 g/mol

Ref: 3D-DJB40076