CAS 85375-15-1

3-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-buten-1-yl)-, hydrochloride (1:1)

Description:

3-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-buten-1-yl)-, hydrochloride (1:1), with CAS number 85375-15-1, is a chemical compound characterized by its piperidine ring structure, which is a six-membered nitrogen-containing heterocycle. This compound features a carboxylic acid functional group, contributing to its acidic properties, and a substituted butenyl chain with two phenyl groups, which enhances its lipophilicity and potential biological activity. The hydrochloride form indicates that the compound is a salt, which typically improves its solubility in water and stability. This compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry. Its structural features suggest potential interactions with biological targets, and it may be studied for applications in drug development. As with many organic compounds, proper handling and safety measures should be observed due to its chemical nature. Further research may be necessary to fully elucidate its properties and potential uses in various fields, including pharmaceuticals and materials science.

Formula: C₂₂H₂₅NO₂·ClH

InChI: InChI=1S/C22H25NO2.ClH/c24-22(25)20-13-7-15-23(17-20)16-8-14-21(18-9-3-1-4-10-18)19-11-5-2-6-12-19;/h1-6,9-12,14,20H,7-8,13,15-17H2,(H,24,25);1H

InChI key: InChIKey=SNGGBKYQZVAQKA-UHFFFAOYSA-N

SMILES: C(=CCCN1CC(C(O)=O)CCC1)(C2=CC=CC=C2)C3=CC=CC=C3.Cl

Synonyms:

• 1-(4,4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride
• 1-(4,4-Diphenylbut-3-En-1-Yl)Piperidine-3-Carboxylic Acid Hydrochloride
• 3-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-buten-1-yl)-, hydrochloride (1:1)
• 3-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-butenyl)-, hydrochloride
• 4-(3-Carboxypiperidine)-1,1-diphenyl-1-butene hydrochloride
• Skf 89976A

SKF89976A (hydrochloride)

CAS: 85375-15-1

Formula: C₂₂H₂₆ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 371.9003

Ref: IN-DA003CY1

SKF89976A hydrochloride

CAS: 85375-15-1

SKF89976A hydrochloride

Purity: ≥98%

Molecular weight: 371.9g/mol

Ref: 54-BUP06731

SKF-89976A

CAS: 85375-15-1

Formula: C₂₂H₂₅NO₂·HCl

Molecular weight: 371.90

Ref: 7W-GL3953

SKF89976A hydrochloride

CAS: 85375-15-1

SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) and

Formula: C₂₂H₂₆ClNO₂

Purity: 98.02%

Color and Shape: Solid

Molecular weight: 371.9

Ref: TM-T12930

1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride

CAS: 85375-15-1

Formula: C₂₂H₂₆ClNO₂

Purity: 98%

Molecular weight: 371.91

Ref: 10-F235523

SKF-89976A

Controlled Product

CAS: 85375-15-1

Formula: C₂₂H₂₅NO₂•HCl

Color and Shape: Neat

Molecular weight: 371.9

Ref: TR-S550003

SKF-89976A

CAS: 85375-15-1

SKF-89976A is a potent, selective inhibitor of the uptake of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) into synaptic vesicles. SKF-89976A has been shown to inhibit the uptake of GABA and diazepam in rat brain synaptosomes and to have antiepileptic activity in rats. It also binds to GABA receptors with low affinity. SKF-89976A has been localized to granule cell axons, where it inhibits GABA release, and to presynaptic terminals, where it inhibits GABA uptake. SKF-89976A is expressed in animals as well as in human tissues.
BR>BR>
SKF-89976A was discovered by scientists at SmithKline Beecham Pharmaceuticals (now GlaxoSmithKline) who were looking for drugs that could raise seizure threshold levels during clinical trials on epilepsy patients.BR>BR>
The drug was

Formula: C₂₂H₂₅NO₂·HCl

Purity: Min. 95%

Molecular weight: 371.9 g/mol

Ref: 3D-KDA37515