CAS 85378-82-1

2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, hydrochloride (1:1), (1S,2R)-

Description:

2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, hydrochloride (1:1), (1S,2R)- is a chemical compound characterized by its complex structure, which includes a naphthalene ring fused with a tetrahydro derivative and various functional groups. This compound features a methoxy group and a propyl substituent on the nitrogen atom, contributing to its unique properties. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, which enhances its bioavailability for potential pharmaceutical applications. The stereochemistry indicated by (1S,2R) suggests specific spatial arrangements of atoms, which can significantly influence the compound's biological activity and interactions. This compound may exhibit various pharmacological effects, making it of interest in medicinal chemistry. However, detailed studies on its toxicity, efficacy, and specific applications would be necessary to fully understand its potential uses and safety profile. As with many chemical substances, handling should be conducted with care, following appropriate safety protocols.

Formula: C₁₅H₂₃NO·ClH

InChI: InChI=1S/C15H23NO.ClH/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3;/h5-7,11,14,16H,4,8-10H2,1-3H3;1H/t11-,14+;/m0./s1

InChI key: InChIKey=KIRYNZFMOLYYQB-YECZQDJWSA-N

SMILES: O(C)C1=C2C([C@H](C)[C@H](NCCC)CC2)=CC=C1.Cl

Synonyms:

• 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, hydrochloride, (1S,2R)-
• 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, hydrochloride (1:1), (1S,2R)-
• 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, hydrochloride, (1S-cis)-

AJ-76 (hydrochloride)

CAS: 85378-82-1

Formula: C₁₅H₂₄ClNO

Purity: 98%

Molecular weight: 269.8102

Ref: IN-DA01E5GY

AJ-76 (hydrochloride)

CAS: 85378-82-1

AJ-76 (hydrochloride)

Purity: 98%

Molecular weight: 269.82g/mol

Ref: 54-OR1034247

AJ-76 hydrochloride

CAS: 85378-82-1

AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.

Formula: C₁₅H₂₄ClNO

Color and Shape: Solid

Molecular weight: 269.81

Ref: TM-T84695