CAS 854107-55-4

Ponesimod

Description:

Ponesimod is a selective sphingosine-1-phosphate receptor modulator, primarily targeting the S1P1 receptor. It is designed for the treatment of autoimmune diseases, particularly multiple sclerosis. The compound functions by modulating lymphocyte circulation, effectively reducing the number of circulating lymphocytes and thereby mitigating inflammatory responses associated with autoimmune conditions. Ponesimod exhibits high oral bioavailability and a favorable pharmacokinetic profile, allowing for once-daily dosing. Its chemical structure includes a pyrimidine core, contributing to its receptor selectivity and activity. The substance has undergone various clinical trials to assess its efficacy and safety, demonstrating a potential to improve patient outcomes in autoimmune disorders. As with many pharmacological agents, side effects may occur, and its use should be monitored by healthcare professionals. Overall, Ponesimod represents a significant advancement in targeted therapies for managing chronic inflammatory diseases.

Formula: C₂₃H₂₅ClN₂O₄S

Synonyms:

• Act-128800
• 5-[3-Chloro-4-[((2R)-2,3-dihydroxypropyl)oxy]benz-(Z)-ylidene]-2-((Z)-propylimino)-3-(o-tolyl)thiazolidin-4-one
• CS-2110
• 4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]Methylene]-3-(2-Methylphenyl)-2-(propyliMino)-, (2Z,5Z)-
• PONESIMOD,ACT-128800
• CS-2358
• (5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one
• (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one
• PonesiMod
• ACT128800;ACT 128800;ACT-128800

(2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one

CAS: 854107-55-4

Formula: C₂₃H₂₅ClN₂O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.9736

Ref: IN-DA00G3RG

Ponesimod

CAS: 854107-55-4

Ponesimod

Purity: ≥98%

Molecular weight: 460.97g/mol

Ref: 54-BUP08149

Ponesimod

CAS: 854107-55-4

Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.

Formula: C₂₃H₂₅ClN₂O₄S

Purity: 99.42% - 99.96%

Color and Shape: Solid

Molecular weight: 460.97

Ref: TM-T3258

Ponesimod

CAS: 854107-55-4

Formula: C₂₃H₂₅ClN₂O₄S

Molecular weight: 460.97

Ref: 4Z-P-458001

Ponesimod

CAS: 854107-55-4

Sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator; for MS and psoriasis

Formula: C₂₃H₂₅ClN₂O₄S

Purity: Min. 95%

Molecular weight: 460.97 g/mol

Ref: 3D-BP175283